Biosimilar参照抗体

在生物药研发中，抗体药物研发无疑是最受关注的焦点，是增长最快的细分领域之一，已成为生物药中最重要的一大品类。在抗体药物开发过程中，头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。

缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统，重组表达了众多热门靶点的biosimilar参照抗体，便利广大科研工作者进行相关开发过程中的对比研究，同时也可以辅佐验证靶点蛋白的功能活性。

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产品数据展示：

 

活性蛋白检测

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能检测对比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar参照抗体列表

FC-BME100079 BM141 1 flow TSHR

Biosimilar reference antibodies

Anti-TSHR (M22) mAb

SKU:  BME100079     Target:  TSHR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100078 BM128 FAC TransfectedWithB7 H4 Fig2

Biosimilar reference antibodies

Anti-B7-H4(alsevalimab biosimilar) mAb

SKU:  BME100078     Target:  B7H4

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100077 Anti SELPcrizanlizumab biosimilar mAb FLOW Fig1

Biosimilar reference antibodies

Anti-SELP(crizanlizumab biosimilar) mAb

SKU:  BME100077     Target:  SELP

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100068 BM50 flow DLL3

Biosimilar reference antibodies

Anti-DLL3(Rovalpituzumab biosimilar) mAb

SKU:  BME100068     Target:  DLL3

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100065 BM29 flow GITR

Biosimilar reference antibodies

Anti-GITR(ragifilimab biosimilar) mAb

SKU:  BME100065     Target:  GITR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100063 fig1

Biosimilar reference antibodies

Anti-CCR8(10A11) mAb

SKU:  BME100063     Target:  CCR8

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-Anti BME100075 CLDN18.2 mAb zolbetuximab

Biosimilar reference antibodies

Anti-CLDN18.2 (zolbetuximab biosimilar) mAb

SKU:  BME100075     Target:  CLDN18.2

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100074 BM129 FAC TransfectedWithITGA4 Fig.1

Biosimilar reference antibodies

Anti-ITGA4 (natalizumab biosimilar) mAb

SKU:  BME100074     Target:  ITGA4

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100058 Anti TNFSF11 denosumab biosimilarmAb FLOW Fig1

Biosimilar reference antibodies

Anti-TNFSF11 (denosumab biosimilar)mAb

SKU:  BME100058     Target:  TNFSF11

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100062 Anti LAG3 mAbrelatlimab biosimilar FLOW Fig2

Biosimilar reference antibodies

Anti-LAG3 (relatlimab biosimilar)mAb

SKU:  BME100062     Target:  LAG3

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100061 Anti VEGFA mAb bevacizumab biosimilar ELISA Fig1

Biosimilar reference antibodies

Anti-VEGFA(bevacizumab biosimiar) mAb

SKU:  BME100061     Target:  VEGFA

Application:  ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100060 Anti VEGFR2 mAbramucirumab biosimilar FLOW Fig1

Biosimilar reference antibodies

Anti-VEGFR2 (ramucirumab biosimilar)mAb

SKU:  BME100060     Target:  VEGFR2

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100056 Anti TNF mAbAdalimumab biosimilar FLOW Fig2

Biosimilar reference antibodies

Anti-TNFa(Adalimumab biosimilar) mAb

SKU:  BME100056     Target:  TNFA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100054 Anti BTLA mAbicatolimab biosimilar FLOW Fig2

Biosimilar reference antibodies

Anti-BTLA (icatolimab biosimilar)mAb

SKU:  BME100054     Target:  BTLA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100053 Anti OX40 mAbivuxolimab biosimilar FLOW Fig1

Biosimilar reference antibodies

Anti-OX40( ivuxolimab biosimilar)mAb

SKU:  BME100053     Target:  OX40

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100052 Anti IL 4RAmAbdupilumab biosimilar FLOW Fig2

Biosimilar reference antibodies

Anti-IL-4RA (dupilumab biosimilar)mAb

SKU:  BME100052     Target:  IL4RA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100051 CD19 Fig.2 Elisa 1

Biosimilar reference antibodies

Anti-CD19 (inebilizumab biosimilar)mAb

SKU:  BME100051     Target:  CD19

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100045 Anti BAFFR ianalumab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-BAFFR (ianalumab biosimilar) mAb

SKU:  BME100045     Target:  BAFF-R

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100044 Anti BAFFbelimumab biosimilarmAb FLOW Fig2

Biosimilar reference antibodies

Anti-BAFF (belimumab biosimilar) mAb

SKU:  BME100044     Target:  BAFF

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100043 Anti IL2RA basiliximab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-IL2RA (basiliximab biosimilar) mAb

SKU:  BME100043     Target:  IL2RA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100042 Anti CD40L ruplizumab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-CD40 Ligand (ruplizumab biosimilar) mAb

SKU:  BME100042     Target:  CD40 Ligand

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100041 Anti IL6R tocilizumab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-IL6R (tocilizumab biosimilar) mAb

SKU:  BME100041     Target:  IL6R

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100037 Anti 4 1BB mAbutomilumab biosimilar FLOW Fig2

Biosimilar reference antibodies

Anti-4-1BB (utomilumab biosimilar) mAb

SKU:  BME100037     Target:  4-1BB

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100036 BM52 FAC TransfectedWithICAM1 Fig.2

Biosimilar reference antibodies

Anti-ICAM-1 (bersanlimab biosimilar) mAb

SKU:  BME100036     Target:  ICAM-1

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100038 Anti IL17RA brodalumab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-IL17RA (brodalumab biosimilar) mAb

SKU:  BME100038     Target:  IL17RA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100031 BM58 FAC TransfectedWithTweakR Fig2

Biosimilar reference antibodies

Anti-TweakR (enavatuzumab biosimilar) mAb

SKU:  BME100031     Target:  TweakR

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100030 Anti CD52 alemtuzumab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-CD52 (alemtuzumab biosimilar) mAb

SKU:  BME100030     Target:  CD52

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100029 Anti CD22 pinatuzumab vedotin biosimilar mAb FLOW Fig2 A

Biosimilar reference antibodies

Anti-CD22 (pinatuzumab biosimilar) mAb

SKU:  BME100029     Target:  CD22

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100028 Anti BCMA belantamab biosimilarmAb FLOW Fig2

Biosimilar reference antibodies

Anti-BCMA (belantamab biosimilar) mAb

SKU:  BME100028     Target:  BCMA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100027 BM77 3 FAC TransfectedWithTIGIT Fig2

Biosimilar reference antibodies

Anti-TIGIT (vibostolimab biosimilar) mAb

SKU:  BME100027     Target:  TIGIT

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100026 BM77 2 FAC TransfectedWithTIGIT Fig2

Biosimilar reference antibodies

Anti-TIGIT (tiragolumab biosimilar) mAb

SKU:  BME100026     Target:  TIGIT

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100025 CD20 Fig.1 FC 1

Biosimilar reference antibodies

Anti-CD20 (rituximab biosimilar) mAb

SKU:  BME100025     Target:  CD20

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00