Biosimilar参照抗体

在生物药研发中，抗体药物研发无疑是最受关注的焦点，是增长最快的细分领域之一，已成为生物药中最重要的一大品类。在抗体药物开发过程中，头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。

缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统，重组表达了众多热门靶点的biosimilar参照抗体，便利广大科研工作者进行相关开发过程中的对比研究，同时也可以辅佐验证靶点蛋白的功能活性。

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产品数据展示：

活性蛋白检测

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能检测对比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar参照抗体列表

FC-BME100040 Anti CA9 girentuximab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-CA9 (girentuximab biosimilar) mAb

SKU: BME100040 Target: CA9

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100039 BM80 FAC TransfectedWithNKG2DDAP10 Fig2

Biosimilar reference antibodies

Anti-NKG2D (tesnatilimab biosimilar) mAb

SKU: BME100039 Target: NKG2D

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100024 Anti TIGIT etigilimab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-TIGIT (etigilimab biosimilar) mAb

SKU: BME100024 Target: TIGIT

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100022 Anti CTLA4 ipilimumab biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-CTLA-4 (ipilimumab biosimilar) mAb

SKU: BME100022 Target: CTLA-4

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100021 Anti Mesothelin amatuximab biosimilar mAb FLOW Fig2 A

Biosimilar reference antibodies

Anti-Mesothelin (amatuximab biosimilar) mAb

SKU: BME100021 Target: MSLN

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100020 Anti CD40 iscalimab biosimilarmAb FLOW Fig2 A

Biosimilar reference antibodies

Anti-CD40 (iscalimab biosimilar) mAb

SKU: BME100020 Target: CD40

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100019 Anti EPHA3 ifabotuzumab biosimilar mAb FLOW Fig2 A

Biosimilar reference antibodies

Anti-EPHA3 (ifabotuzumab biosimilar) mAb

SKU: BME100019 Target: EPHA3

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100018 Anti CD27 varlilumab biosimilar mAb FLOW Fig3 A

Biosimilar reference antibodies

Anti-CD27 (varlilumab biosimilar) mAb

SKU: BME100018 Target: CD27

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100014 Anti CD138indatuximab ravtansine biosimilar mAb FLOW Fig1 A

Biosimilar reference antibodies

Anti-CD138 (indatuximab biosimilar) mAb

SKU: BME100014 Target: CD138

Application: Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100013 ELISA1 CR3022 Figure1

Biosimilar reference antibodies

Anti-SARS-CoV (CR3022) mAb

SKU: BME100013 Target: SARS

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100012 Anti ICOS vopratelimab biosimilar mAb Elisa fig1

Biosimilar reference antibodies

Anti-ICOS (vopratelimab biosimilar) mAb

SKU: BME100012 Target: ICOS

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100011 Anti SARS CoV 2 CB6 mAb Elisa fig1

Biosimilar reference antibodies

Anti-SARS-CoV-2 (CB6 biosimilar) mAb

SKU: BME100011 Target: SARS

Application: ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100009 Anti PDL1 atezolizumab biosimilar mAb Elisa fig1

Biosimilar reference antibodies

Anti-PDL1 (atezolizumab biosimilar) mAb

SKU: BME100009 Target: PDL1

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100008 TIM3 Fig.2 FC 1

Biosimilar reference antibodies

Anti-TIM3 (cobolimab biosimilar) mAb

SKU: BME100008 Target: TIM3

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100007 Anti IL6 siltuximab biosimilar mAb Elisa fig1

Biosimilar reference antibodies

Anti-IL6 (siltuximab biosimilar) mAb

SKU: BME100007 Target: IL6

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100006 Anti PD 1 pembrolizumab biosimilar mAb Elisa fig1 1

Biosimilar reference antibodies

Anti-PD-1 (pembrolizumab biosimilar) mAb

SKU: BME100006 Target: PD-1

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100004 Anti CD38 daratumumab biosimilar mAb Elisa fig1

Biosimilar reference antibodies

Anti-CD38 (daratumumab biosimilar) mAb

SKU: BME100004 Target: CD38

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-HEL Mouse IgG2a-Kappa Isotype control mAb

SKU: BME100273 Target: HEL

Application: N/A

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-HEL Mouse IgG1-Kappa Isotype control mAb

SKU: BME100272 Target: HEL

Application: N/A

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-HEL Human IgG1(L234A/L235A)-Kappa Isotype control mAb

SKU: BME100271 Target: HEL

Application: N/A

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

PE-conjugated Anti-TRBV9(seniprutug biosimilar) mAb

SKU: BME100762P Target: TRBV9

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-KLK2(alpitatug biosimilar) mAb

SKU: BME100746P Target: KLK2

Application: Flow Cyt

Price: 100 test ￥1360.00

FC-bme100683p cd19 fc1

Biosimilar reference antibodies

PE-conjugated Anti-CD19(tafasitamab biosimilar) mAb

SKU: BME100683P Target: CD19

Application: Flow Cyt

Price: 100 test ￥1360.00

FC-bme100657p pd 1 fc1

Biosimilar reference antibodies

PE-conjugated Anti-PD-1(rosnilimab biosimilar) mAb

SKU: BME100657P Target: PD-1

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-EGFR(depatuxizumab biosimilar) mAb

SKU: BME100252P Target: EGFR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-IL1RL2(imsidolimab biosimilar) mAb

SKU: BME100251P Target: IL1RL2

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-EGFR(QD6 biosimilar) mAb

SKU: BME100250P Target: EGFR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-MUC1(PAb-001 biosimilar) mAb

SKU: BME100249P Target: MUC1

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-LEPR(mibavademab biosimilar) mAb

SKU: BME100246P Target: LEPR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-MET(emibetuzumab biosimilar) mAb

SKU: BME100245P Target: MET

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-Her3(seribantumab biosimilar) mAb

SKU: BME100244P Target: HER3

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-ILDR2(bapotulimab biosimilar) mAb

SKU: BME100243P Target: ILDR2

Application: Flow Cyt

Price: 100 test ￥1360.00