Biosimilar参照抗体

在生物药研发中，抗体药物研发无疑是最受关注的焦点，是增长最快的细分领域之一，已成为生物药中最重要的一大品类。在抗体药物开发过程中，头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。

缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统，重组表达了众多热门靶点的biosimilar参照抗体，便利广大科研工作者进行相关开发过程中的对比研究，同时也可以辅佐验证靶点蛋白的功能活性。

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产品数据展示：

 

活性蛋白检测

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能检测对比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar参照抗体列表

FC-BME100148 BM389 Anti OSMR FACS Fig1

Biosimilar reference antibodies

Anti-OSMR(vixarelimab biosimilar) mAb

SKU:  BME100148     Target:  OSMR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100147 BM300 1 Anti GPC3 ELISA Fig1

Biosimilar reference antibodies

Anti-GPC3(Hu9F2) mAb

SKU:  BME100147     Target:  GPC3

Application:  ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100142 BM413 Anti GCGR FACS Fig1

Biosimilar reference antibodies

Anti-GCGR(volagidemab biosimilar) mAb

SKU:  BME100142     Target:  GCGR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100136 BM191 Anti APP FACS Fig1

Biosimilar reference antibodies

Anti-APP(aducanumab biosimilar) mAb

SKU:  BME100136     Target:  APP

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100134 BM446 Anti KIR2DL2 FACS Fig1

Biosimilar reference antibodies

Anti-KIR2DL2(lirilumab biosimilar) mAb

SKU:  BME100134     Target:  KIR2DL2

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100145 BM489 Anti LILRB2 FACS Fig2

Biosimilar reference antibodies

Anti-LILRB2 (MK-4830) mAb

SKU:  BME100145     Target:  LILRB2

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100137 BM451 Anti IL17A FACS Fig1

Biosimilar reference antibodies

Anti-IL17A(secukinumab biosimilar) mAb

SKU:  BME100137     Target:  IL17A

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100133 BM439 Anti CXCL10 FACS Fig1

Biosimilar reference antibodies

Anti-CXCL10(eldelumab biosimilar) mAb

SKU:  BME100133     Target:  CXCL10

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100132 BM426 Anti IL20 FACS Fig1

Biosimilar reference antibodies

Anti-IL20(fletikumab biosimilar) mAb

SKU:  BME100132     Target:  IL20

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100131 BM307 Anti FLT1 FACS Fig3

Biosimilar reference antibodies

Anti-FLT1(icrucumab biosimilar) mAb

SKU:  BME100131     Target:  FLT1

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100130 BM177 Anti GM CSF FACS Fig2

Biosimilar reference antibodies

Anti-GM-CSF(plonmarlimab biosimilar) mAb

SKU:  BME100130     Target:  GM-CSF

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100128 BM134 Anti PSMA FACS Fig2

Biosimilar reference antibodies

Anti-PSMA(rosopatamab biosimilar) mAb

SKU:  BME100128     Target:  PSMA

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100125 BM455 Anti CCL2 FACS Fig1

Biosimilar reference antibodies

Anti-CCL2(carlumab biosimilar) mAb

SKU:  BME100125     Target:  CCL2

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100113 BM283 Anti LIV1 ELISA Fig1

Biosimilar reference antibodies

Anti-LIV-1(ladiratuzumab biosimilar) mAb

SKU:  BME100113     Target:  LIV-1

Application:  ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100112 BM277 Anti TSLP FACS Fig2

Biosimilar reference antibodies

Anti-TSLP(tezepelumab biosimilar) mAb

SKU:  BME100112     Target:  TSLP

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100107 BM160 Anti DKK1 FACS Fig1

Biosimilar reference antibodies

Anti-DKK1(sirexatamab biosimilar) mAb

SKU:  BME100107     Target:  DKK1

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100095 BM153 Anti PCSK9 FACS Fig1

Biosimilar reference antibodies

Anti-PCSK9(bococizumab biosimilar) mAb

SKU:  BME100095     Target:  PCSK9

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100105 BM148 Anti CCN2 FACS Fig1

Biosimilar reference antibodies

Anti-CCN2(pamrevlumab biosimilar) mAb

SKU:  BME100105     Target:  CCN2

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100129 BM175 Anti CD73 FACS Fig1

Biosimilar reference antibodies

Anti-CD73(uliledlimab biosimilar) mAb

SKU:  BME100129     Target:  CD73

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100127 BM488 Anti SSTR2 FACS Fig2

Biosimilar reference antibodies

Anti-SSTR2(tidutamab biosimilar) mAb

SKU:  BME100127     Target:  SSTR2

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100122 BM485 Anti IL9 FACS Fig2

Biosimilar reference antibodies

Anti-IL9(enokizumab biosimilar) mAb

SKU:  BME100122     Target:  IL9

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100117 BM327 Anti IFNAR1 FACS Fig3

Biosimilar reference antibodies

Anti-IFNAR1(anifrolumab biosimilar) mAb

SKU:  BME100117     Target:  IFNAR1

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100116 BM171 Anti IL1B FACS Fig2

Biosimilar reference antibodies

Anti-IL1B(canakinumab biosimilar) mAb

SKU:  BME100116     Target:  IL1B

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100115 BM203 1 Anti CCR8 FACS Fig2

Biosimilar reference antibodies

Anti-CCR8(BMS 986340) mAb

SKU:  BME100115     Target:  CCR8

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100120 BM419 Anti C5AR1 FACS Fig1

Biosimilar reference antibodies

Anti-C5AR1(avdoralimab biosimilar) mAb

SKU:  BME100120     Target:  C5AR1

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100119 BM411 Anti NRP1 FACS Fig1

Biosimilar reference antibodies

Anti-NRP1(vesencumab biosimilar) mAb

SKU:  BME100119     Target:  NRP1

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100090 BM268 Anti GDF15 FACS Fig1

Biosimilar reference antibodies

Anti-GDF15(ponsegromab biosimilar) mAb

SKU:  BME100090     Target:  GDF15

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100109 BM183 Anti B7 H5 FACS Fig2

Biosimilar reference antibodies

Anti-B7-H5(onvatilimab biosimilar) mAb

SKU:  BME100109     Target:  B7-H5

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100103 BM140 Anti IL21 ELISA Fig1

Biosimilar reference antibodies

Anti-IL21(avizakimab biosimilar) mAb

SKU:  BME100103     Target:  IL21

Application:  ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100101 BM296 Anti CXCR4 FACS Fig1

Biosimilar reference antibodies

Anti-CXCR4(ulocuplumab biosimilar) mAb

SKU:  BME100101     Target:  CXCR4

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100100 BM293 Anti CEACAM6 FACS Fig1

Biosimilar reference antibodies

Anti-CEACAM6(tinurilimab biosimilar) mAb

SKU:  BME100100     Target:  CEACAM6

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100094 BM9 1 FAC TransfectedWithCD19 Fig1

Biosimilar reference antibodies

Anti-CD19(FMC63 biosimilar) mAb

SKU:  BME100094     Target:  CD19

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00