Common Name | IMMU-130, hMN-14-SN-38, hMN-14-SN-38 ADC, hMN14-CL-SN-38, hMN14-SN-38 |
---|---|
Synonyms | CEACAM-5;CD66e;CEA;Meconium antigen 100 |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000 |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Host Species | Humanized |
IgG type | IgG1 |
Reactivity | Human |
Target | |
Uniprot ID | P06731 |
Description | Anti-CEACAM5 (labetuzumab biosimilar) mAb |
Delivery | In Stock |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
Usage | Research use only |
Anti-CEACAM5 (labetuzumab biosimilar) mAb
Price: 50 μg ¥800.00 ; 100 μg ¥1500.00
Product Data
图片
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CEACAM5, His tagged protein PME100071 can bind Anti-CEACAM5 Neutralizing antibody(BME100035) in a linear range of 2.56-320 ng/ml.
Figure 2. Flow cytometry analysis with Anti-CEACAM5 (labetuzumab ) on Expi293 cells transfected with human CEACAM5 (Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram).
Figure 3. Flow cytometry analysis of antigen binding of anti-human CEACAM5 mAb(BME100035).
(A) A clear peak shift of BME100035 was seen compared to the control when incubated with CEACAM5-expressing MKN45 cells, indicating strong binding of BME100035 to CEACAM5. Antibodies were incubated at 2 μg/mL.
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