Biosimilar参照抗体

在生物药研发中，抗体药物研发无疑是最受关注的焦点，是增长最快的细分领域之一，已成为生物药中最重要的一大品类。在抗体药物开发过程中，头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。

缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统，重组表达了众多热门靶点的biosimilar参照抗体，便利广大科研工作者进行相关开发过程中的对比研究，同时也可以辅佐验证靶点蛋白的功能活性。

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产品数据展示：

 

活性蛋白检测

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能检测对比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar参照抗体列表

FC-BME100167 ALPP Fig.1 FC 1

Biosimilar reference antibodies

Anti-ALPP(TCRCure A06 Biosimilar) mAb

SKU:  BME100167     Target:  ALPP

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100166 CGRPR Fig.1 FC 1

Biosimilar reference antibodies

Anti-CGRPR(Erenumab biosimilar) mAb

SKU:  BME100166     Target:  CGRPR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100165 Mesothelin Fig.1 FC 1

Biosimilar reference antibodies

Anti-Mesothelin VHH-human IgG1 Fc

SKU:  BME100165     Target:  Mesothelin

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100164 IL23A Fig.1 Elisa 1

Biosimilar reference antibodies

Anti-IL23A(guselkumab biosimilar) mAb

SKU:  BME100164     Target:  IL23A

Application:  ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100143 MASP2 Fig.1 FC 1

Biosimilar reference antibodies

Anti-MASP2(narsoplimab biosimilar) mAb

SKU:  BME100143     Target:  MASP2

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100163 FOLR1 Fig.1 FC 1

Biosimilar reference antibodies

Anti-FOLR1(farletuzumab biosimilar) mAb

SKU:  BME100163     Target:  FOLR1

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100162 KLRG1 Fig.1 FC 1

Biosimilar reference antibodies

Anti-KLRG1(ulviprubart biosimilar) mAb

SKU:  BME100162     Target:  KLRG1

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100160 CD20 Fig.1 FC 1

Biosimilar reference antibodies

Anti-CD20 (obinutuzumab biosimilar) mAb

SKU:  BME100160     Target:  CD20

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100146 ITGAV Fig.1 FC 1 1

Biosimilar reference antibodies

Anti-ITGAV(abituzumab biosimilar) mAb

SKU:  BME100146     Target:  ITGAV

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100110 TLR2 Fig.1 FC 1

Biosimilar reference antibodies

Anti-TLR2(tomaralimab biosimilar) mAb

SKU:  BME100110     Target:  TLR2

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100159 BM143 Anti TM4SF1 FACS Fig1

Biosimilar reference antibodies

Anti-TM4SF1 (AGX101 biosimilar) mAb

SKU:  BME100159     Target:  TM4SF1

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100158 BM108 2 Anti 5T4 FACS Fig1

Biosimilar reference antibodies

Anti-5T4 (GEN-1044 biosimilar) mAb

SKU:  BME100158     Target:  5T4

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100157 BM108 1 Anti 5T4 FACS Fig1

Biosimilar reference antibodies

Anti-5T4 (H8 biosimilar) mAb

SKU:  BME100157     Target:  5T4

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100156 BM199 Anti CD45 FACS Fig1 2

Biosimilar reference antibodies

Anti-CD45 (apamistamab biosimilar) mAb

SKU:  BME100156     Target:  CD45

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100155 BM491 Anti CLEC4C ELISA Fig1 1

Biosimilar reference antibodies

Anti-CLEC4C (litifilimab biosimilar) mAb

SKU:  BME100155     Target:  CLEC4C

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100151 BM490 Anti ENPP3 FACS Fig1

Biosimilar reference antibodies

Anti-ENPP3(XENP28278) mAb

SKU:  BME100151     Target:  ENPP3

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100138 BM409 Anti TFRC FACS Fig1

Biosimilar reference antibodies

Anti-TFRC(pabinafusp alfa biosimilar) mAb

SKU:  BME100138     Target:  TFRC

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100124 CD142 Fig.1 Elisa 1

Biosimilar reference antibodies

Anti-CD142(tisotumab biosimilar) mAb

SKU:  BME100124     Target:  CD142

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100153 BM15 1 Anti PDL1 FACS Fig1

Biosimilar reference antibodies

Anti-PDL1 (durvalumab biosimilar) mAb

SKU:  BME100153     Target:  PDL1

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100149 BM212 Anti HTRA1 FACS Fig1

Biosimilar reference antibodies

Anti-HTRA1(galegenimab biosimilar) mAb

SKU:  BME100149     Target:  HTRA1

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100141 BM464 Anti IFNG FACS Fig1

Biosimilar reference antibodies

Anti-IFNG(emapalumab biosimilar) mAb

SKU:  BME100141     Target:  IFNG

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100150 BM274 Anti GP6 FACS Fig1

Biosimilar reference antibodies

Anti-GP6(glenzocimab biosimilar) mAb

SKU:  BME100150     Target:  GP6

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100148 BM389 Anti OSMR FACS Fig1

Biosimilar reference antibodies

Anti-OSMR(vixarelimab biosimilar) mAb

SKU:  BME100148     Target:  OSMR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100147 BM300 1 Anti GPC3 ELISA Fig1

Biosimilar reference antibodies

Anti-GPC3(Hu9F2) mAb

SKU:  BME100147     Target:  GPC3

Application:  ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100142 BM413 Anti GCGR FACS Fig1

Biosimilar reference antibodies

Anti-GCGR(volagidemab biosimilar) mAb

SKU:  BME100142     Target:  GCGR

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100136 BM191 Anti APP FACS Fig1

Biosimilar reference antibodies

Anti-APP(aducanumab biosimilar) mAb

SKU:  BME100136     Target:  APP

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100134 BM446 Anti KIR2DL2 FACS Fig1

Biosimilar reference antibodies

Anti-KIR2DL2(lirilumab biosimilar) mAb

SKU:  BME100134     Target:  KIR2DL2

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100145 BM489 Anti LILRB2 FACS Fig2

Biosimilar reference antibodies

Anti-LILRB2 (MK-4830) mAb

SKU:  BME100145     Target:  LILRB2

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100137 BM451 Anti IL17A FACS Fig1

Biosimilar reference antibodies

Anti-IL17A(secukinumab biosimilar) mAb

SKU:  BME100137     Target:  IL17A

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100133 BM439 Anti CXCL10 FACS Fig1

Biosimilar reference antibodies

Anti-CXCL10(eldelumab biosimilar) mAb

SKU:  BME100133     Target:  CXCL10

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100132 BM426 Anti IL20 FACS Fig1

Biosimilar reference antibodies

Anti-IL20(fletikumab biosimilar) mAb

SKU:  BME100132     Target:  IL20

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100131 BM307 Anti FLT1 FACS Fig3

Biosimilar reference antibodies

Anti-FLT1(icrucumab biosimilar) mAb

SKU:  BME100131     Target:  FLT1

Application:  ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00