Biosimilar参照抗体

在生物药研发中,抗体药物研发无疑是最受关注的焦点,是增长最快的细分领域之一,已成为生物药中最重要的一大品类。在抗体药物开发过程中,头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。

缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统,重组表达了众多热门靶点的biosimilar参照抗体,便利广大科研工作者进行相关开发过程中的对比研究,同时也可以辅佐验证靶点蛋白的功能活性。

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产品数据展示:

 

活性蛋白检测

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能检测对比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar参照抗体列表

SKU:  BME100241P     Target:  IL1RAP

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100240P     Target:  IL13RA1

Application:  Flow Cyt

Price: 100 test ¥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD98(HuM23 biosimilar) mAb

SKU:  BME100238P     Target:  CD98

Application:  Flow Cyt

Price: 100 test ¥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-LILRB4(MK-0482 biosimilar) mAb

SKU:  BME100237P     Target:  LILRB4

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100236P     Target:  PTK7

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100235P     Target:  IL1RL2

Application:  Flow Cyt

Price: 100 test ¥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CDH6(AMT-707 biosimilar) mAb

SKU:  BME100234P     Target:  CDH6

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100233P     Target:  CDH17

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100232P     Target:  CDH6

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100231P     Target:  IL31RA

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100230P     Target:  ADAM9

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100229P     Target:  NKG2D

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100228P     Target:  ACVR2B

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100227P     Target:  CRTAM

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100226P     Target:  CRTAM

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100225P     Target:  CD79B

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100222P     Target:  TNFSF15

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100221P     Target:  IL5RA

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100220P     Target:  FGFR3

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100219P     Target:  CD39

Application:  Flow Cyt

Price: 100 test ¥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD73(BMS 986179) mAb

SKU:  BME100218P     Target:  CD73

Application:  Flow Cyt

Price: 100 test ¥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD73(oleclumab biosimilar) mAb

SKU:  BME100217P     Target:  CD73

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100216P     Target:  TEM1

Application:  Flow Cyt

Price: 100 test ¥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-MUC18(AMT 253 biosimilar) mAb

SKU:  BME100215P     Target:  MUC18

Application:  Flow Cyt

Price: 100 test ¥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD6(itolizumab biosimilar) mAb

SKU:  BME100214P     Target:  CD6

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100213P     Target:  GM-CSFR

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100212P     Target:  HEL

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100209P     Target:  GIPR

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100059P     Target:  MUC1

Application:  Flow Cyt

Price: 100 test ¥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-LY6E(RG7841) mAb

SKU:  BME100224P      Target:  LY6E

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100211P     Target:  HEL

Application:  Flow Cyt

Price: 100 test ¥1360.00

SKU:  BME100210P     Target:  HEL

Application:  Flow Cyt

Price: 100 test ¥1360.00