缔码生物创新性的兔重组单克隆抗体平台，聚焦肿瘤免疫靶点，使用功能活性充分验证的重组蛋白作为抗原免疫兔子，直接从阳性兔B细胞中克隆IgG，重组表达进行流式验证。这一技术不仅大大缩短了研发的时间，也让我们能够直接获得IgG的基因序列信息，而无需担心杂交瘤细胞丢失。
已成功开发出5000+兔单抗产品，覆盖500余种靶点。
产品均经过ELISA或流式验证，还可开发WB、IHC、IF、荧光标记等应用。
兔抗体基因库具有更高多样性，更高亲和力，表位覆盖更广。
兔单抗、人兔嵌合抗体、人源化抗体等。
缔码基于单B细胞技术的兔单抗发现平台开发出来的抗体成药性高。
可提供多标签、多种属及大规格包装定制。
缔码生物拥有独创的DIMA mAbs重组单克隆抗体开发平台，可以在完成动物免疫后直接从外周血中获取阳性B细胞并克隆抗体基因序列。从单只免疫动物中我们可以得到上万个靶点结合阳性B细胞克隆，从中能够更为高效的筛选出具有高特异性、高亲和力重组单克隆抗体。
| 2B4 | 4-1BB | 4-1BB-L | SIRPα |
| B7-H3 | BCMA | CD123 | CD48 |
| CD138 | CD22 | CD27 | GITR Ligand |
| CD28 | CD38 | CD47 | CS1 |
| GPRC5D | CTLA-4 | MSLN | TROP2 |
| GITR | TIM3 | B7-2 | PSCA |
| NKp30 | BTN3A1 | DNAM1 | B7-H2 |
| CD40 |
A) Flow cytometry data of serially titrated Rabbit anti-SIRPα monoclonal antibody (DME100008). The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used. B) Competition assay demonstrating DME100008 blockade of CD47 binding to THP-1 cells. IC50=30.88ng/ml.
Left: Western blot analysis of CD38 protein using Anti-CD38 antibody (Cat. DME100027) at 1:1000 dilution.
Right: Western blot analysis of CD48 protein using Anti-CD48 antibody (SKU# DME100043) at 1/1000 dilution.
Anti-CD27 antibody(DM59), Rabbit mAb (DME100059) at 10µg/ml staining CD27 in Raji cells by IHC (SKU# DME100059);B. DME100059 at 10µg/ml staining CD27 in human tonsil tissue by IHC (SKU# DME100059)
A: The scheme of Anti-BCMA BiTE molecule (Cat. DMB100003). B: Tumor cell killing assay.
Monoclonal Antibodies
SKU: DME100190P Target: PGF
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100189P Target: BCL2L1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100187P Target: IL2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100213P Target: CD24
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100179P Target: CLDN18.2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100169P Target: PDL2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100176P Target: CD10
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100172P Target: CD114
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100170P Target: LIGHT
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100168P Target: MICB
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100167P Target: EPHA2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100153P Target: B7-H6
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100155P Target: CD171
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100156P Target: CD200
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100157P Target: MICA
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100159P Target: NTB-A
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100161P Target: CD5
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100165P Target: CLEC12A
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100146P Target: CD155
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100145P Target: CD46
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100144P Target: CB1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100140P Target: TNFSF12
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100134P Target: CD34
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100131P Target: HVEM
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100118P Target: CD7
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100112P Target: OX40 Ligand
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100109P Target: B7-1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100095P Target: DNAM1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100092P Target: BTN3A1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100088P Target: NKp30
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100087P Target: PSCA
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100084P Target: B7-2
Application: Flow Cyt
Price: 100 test ￥3880.00
