缔码生物创新性的兔重组单克隆抗体平台，聚焦肿瘤免疫靶点，使用功能活性充分验证的重组蛋白作为抗原免疫兔子，直接从阳性兔B细胞中克隆IgG，重组表达进行流式验证。这一技术不仅大大缩短了研发的时间，也让我们能够直接获得IgG的基因序列信息，而无需担心杂交瘤细胞丢失。
已成功开发出5000+兔单抗产品，覆盖500余种靶点。
产品均经过ELISA或流式验证，还可开发WB、IHC、IF、荧光标记等应用。
兔抗体基因库具有更高多样性，更高亲和力，表位覆盖更广。
兔单抗、人兔嵌合抗体、人源化抗体等。
缔码基于单B细胞技术的兔单抗发现平台开发出来的抗体成药性高。
可提供多标签、多种属及大规格包装定制。
缔码生物拥有独创的DIMA mAbs重组单克隆抗体开发平台，可以在完成动物免疫后直接从外周血中获取阳性B细胞并克隆抗体基因序列。从单只免疫动物中我们可以得到上万个靶点结合阳性B细胞克隆，从中能够更为高效的筛选出具有高特异性、高亲和力重组单克隆抗体。
| 2B4 | 4-1BB | 4-1BB-L | SIRPα |
| B7-H3 | BCMA | CD123 | CD48 |
| CD138 | CD22 | CD27 | GITR Ligand |
| CD28 | CD38 | CD47 | CS1 |
| GPRC5D | CTLA-4 | MSLN | TROP2 |
| GITR | TIM3 | B7-2 | PSCA |
| NKp30 | BTN3A1 | DNAM1 | B7-H2 |
| CD40 |
A) Flow cytometry data of serially titrated Rabbit anti-SIRPα monoclonal antibody (DME100008). The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used. B) Competition assay demonstrating DME100008 blockade of CD47 binding to THP-1 cells. IC50=30.88ng/ml.
Left: Western blot analysis of CD38 protein using Anti-CD38 antibody (Cat. DME100027) at 1:1000 dilution.
Right: Western blot analysis of CD48 protein using Anti-CD48 antibody (SKU# DME100043) at 1/1000 dilution.
Anti-CD27 antibody(DM59), Rabbit mAb (DME100059) at 10µg/ml staining CD27 in Raji cells by IHC (SKU# DME100059);B. DME100059 at 10µg/ml staining CD27 in human tonsil tissue by IHC (SKU# DME100059)
A: The scheme of Anti-BCMA BiTE molecule (Cat. DMB100003). B: Tumor cell killing assay.
Monoclonal Antibodies
SKU: DMC100388P Target: EDA
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-ADGRE2 antibody(DMC370); IgG1 Chimeric mAb
SKU: DMC100370P Target: ADGRE2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100366P Target: CFB
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-SLAMF5 antibody(DMC286); IgG1 Chimeric mAb
SKU: DMC100286P Target: SLAMF5
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100285P Target: CD96
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CD162 antibody(DMC283); IgG1 Chimeric mAb
SKU: DMC100283P Target: SELPLG
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-IL11RA antibody(DMC282); IgG1 Chimeric mAb
SKU: DMC100282P Target: IL11RA
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100281P Target: AFP
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100280P Target: CD21
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-Galectin 9 antibody(DMC279); IgG1 Chimeric mAb
SKU: DMC100279P Target: Galectin 9
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-JAM-A antibody(DMC278); IgG1 Chimeric mAb
SKU: DMC100278P Target: JAM-A
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-LGALS1 antibody(DMC277); IgG1 Chimeric mAb
SKU: DMC100277P Target: LGALS1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-VEGFA antibody(DMC276); IgG1 Chimeric mAb
SKU: DMC100276P Target: VEGFA
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100275P Target: ALB
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100274P Target: IL5
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100273P Target: CD36
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CD160 antibody(DMC270); IgG1 Chimeric mAb
SKU: DMC100270P Target: CD160
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100269P Target: CD44
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-VSIG4 antibody(DMC268); IgG1 Chimeric mAb
SKU: DMC100268P Target: VSIG4
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100008P Target: SIRPa
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-IL21R antibody(DMC225); IgG1 Chimeric mAb
SKU: DMC100225P Target: IL21R
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CD112 antibody(DMC224); IgG1 Chimeric mAb
SKU: DMC100224P Target: CD112
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-TREM2 antibody(DMC223); IgG1 Chimeric mAb
SKU: DMC100223P Target: TREM2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-FCGR3A antibody(DMC219); IgG1 Chimeric mAb
SKU: DMC100219P Target: FCGR3A
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100218P Target: IL18RA
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100211P Target: CD43
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100209P Target: NRG1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100208P Target: CXCR3
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100206P Target: IL15RA
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100205P Target: ANGPTL3
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100203P Target: CD99
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DME100194P Target: SCF
Application: Flow Cyt
Price: 100 test ￥3880.00
