缔码生物创新性的兔重组单克隆抗体平台，聚焦肿瘤免疫靶点，使用功能活性充分验证的重组蛋白作为抗原免疫兔子，直接从阳性兔B细胞中克隆IgG，重组表达进行流式验证。这一技术不仅大大缩短了研发的时间，也让我们能够直接获得IgG的基因序列信息，而无需担心杂交瘤细胞丢失。
已成功开发出5000+兔单抗产品，覆盖500余种靶点。
产品均经过ELISA或流式验证，还可开发WB、IHC、IF、荧光标记等应用。
兔抗体基因库具有更高多样性，更高亲和力，表位覆盖更广。
兔单抗、人兔嵌合抗体、人源化抗体等。
缔码基于单B细胞技术的兔单抗发现平台开发出来的抗体成药性高。
可提供多标签、多种属及大规格包装定制。
缔码生物拥有独创的DIMA mAbs重组单克隆抗体开发平台，可以在完成动物免疫后直接从外周血中获取阳性B细胞并克隆抗体基因序列。从单只免疫动物中我们可以得到上万个靶点结合阳性B细胞克隆，从中能够更为高效的筛选出具有高特异性、高亲和力重组单克隆抗体。
| 2B4 | 4-1BB | 4-1BB-L | SIRPα |
| B7-H3 | BCMA | CD123 | CD48 |
| CD138 | CD22 | CD27 | GITR Ligand |
| CD28 | CD38 | CD47 | CS1 |
| GPRC5D | CTLA-4 | MSLN | TROP2 |
| GITR | TIM3 | B7-2 | PSCA |
| NKp30 | BTN3A1 | DNAM1 | B7-H2 |
| CD40 |
A) Flow cytometry data of serially titrated Rabbit anti-SIRPα monoclonal antibody (DME100008). The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used. B) Competition assay demonstrating DME100008 blockade of CD47 binding to THP-1 cells. IC50=30.88ng/ml.
Left: Western blot analysis of CD38 protein using Anti-CD38 antibody (Cat. DME100027) at 1:1000 dilution.
Right: Western blot analysis of CD48 protein using Anti-CD48 antibody (SKU# DME100043) at 1/1000 dilution.
Anti-CD27 antibody(DM59), Rabbit mAb (DME100059) at 10µg/ml staining CD27 in Raji cells by IHC (SKU# DME100059);B. DME100059 at 10µg/ml staining CD27 in human tonsil tissue by IHC (SKU# DME100059)
A: The scheme of Anti-BCMA BiTE molecule (Cat. DMB100003). B: Tumor cell killing assay.
Monoclonal Antibodies
PE-conjugated Anti-SIGLEC7 antibody(DMC475); IgG1 Chimeric mAb
SKU: DMC100475P Target: SIGLEC7
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100473P Target: EMCN
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-EPHA4 antibody(DMC472); IgG1 Chimeric mAb
SKU: DMC100472P Target: EPHA4
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CXCR1 antibody(DMC470); IgG1 Chimeric mAb
SKU: DMC100470P Target: CXCR1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CLEC9A antibody(DMC469); IgG1 Chimeric mAb
SKU: DMC100469P Target: CLEC9A
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CLEC1A antibody(DMC468); IgG1 Chimeric mAb
SKU: DMC100468P Target: CLEC1A
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-TGFBR2 antibody(DMC467); IgG1 Chimeric mAb
SKU: DMC100467P Target: TGFBR2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CSPG4 antibody(DMC466); IgG1 Chimeric mAb
SKU: DMC100466P Target: CSPG4
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100465P Target: CCR1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100462P Target: PRLR
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100461P Target: CLU
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb
SKU: DMC100460P Target: FGFR4
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CD117 antibody(DMC446), IgG1 Chimeric mAb
SKU: DMC100446P Target: CD117
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-SLAMF1 antibody(DMC445); IgG1 Chimeric mAb
SKU: DMC100445P Target: SLAMF1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100444P Target: BST1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CXCR7 antibody(DMC443); IgG1 Chimeric mAb
SKU: DMC100443P Target: CXCR7
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CHODL antibody(DMC442); IgG1 Chimeric mAb
SKU: DMC100442P Target: CHODL
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100441P Target: CD5L
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100440P Target: UPA
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CD62L antibody(DMC439); IgG1 Chimeric mAb
SKU: DMC100439P Target: CD62L
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100436P Target: CD83
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100429P Target: CD81
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100425P Target: CD63
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100424P Target: EREG
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100423P Target: CD2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-IGFBP7 antibody(DMC422); IgG1 Chimeric mAb
SKU: DMC100422P Target: IGFBP7
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-FLT3LG antibody(DMC421); IgG1 Chimeric mAb
SKU: DMC100421P Target: FLT3LG
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100420P Target: PMEL
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-CLEC2D antibody(DMC394); IgG1 Chimeric mAb
SKU: DMC100394P Target: CLEC2D
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-B4GALT1 antibody(DMC392); IgG1 Chimeric mAb
SKU: DMC100392P Target: B4GALT1
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
PE-conjugated Anti-FOLR2 antibody(DMC390); IgG1 Chimeric mAb
SKU: DMC100390P Target: FOLR2
Application: Flow Cyt
Price: 100 test ￥3880.00
Monoclonal Antibodies
SKU: DMC100389P Target: VWF
Application: Flow Cyt
Price: 100 test ￥3880.00
