| Tag | C-Flag&Strep Tag |
|---|---|
| Target | |
| Synonyms | DADR; DRD1A |
| Description | Human DRD1-Strep full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | P21728 |
| Expression Host | HEK293 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Gap junction, Neuroactive ligand-receptor interaction |
| Molecular Weight | The human full length DRD1-Strep protein has a MW of 49.3 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This protein is D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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