| Target | |
|---|---|
| Synonyms | DRD1, D1R, D1A, Dopamine receptor D1A, Dopamine receptor, type 1, DRD1A |
| Description | Recombinant human DRD1 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P21728 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | DRD1(Met1-Arg23) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 28.7 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | DRD1 (Dopamine receptor D1) is a G-protein coupled receptor (GPCR) that primarily couples to Gs proteins, activating adenylyl cyclase and increasing cAMP levels. It is highly expressed in the central nervous system, especially in the striatum and cortex, where it regulates motor control, cognition, reward, and learning. Dysregulation is linked to neurological and psychiatric disorders. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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