| Target | |
|---|---|
| Synonyms | NMA |
| Description | Recombinant human BAMBI Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q13145 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | BAMBI(Glu27-Ala152) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 40.1 kDa after removal of the signal peptide. The apparent molecular mass of BAMBI-hFc is approximately 55-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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