| Target | |
|---|---|
| Synonyms | SLAMF7;CD319;CS1;CRACC;19A;FOAP-12 |
| Description | Recombinant human CS1 protein with C-terminal human Fc and 6×His tag |
| Delivery | In Stock |
| Uniprot ID | Q9NQ25 |
| Expression Host | HEK293 |
| Tag | C-Human Fc and 6×His Tag |
| Molecular Characterization | CS1(Ser23-Asp223) hFc(Glu99-Ala330) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 70 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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