Biosimilar参照抗体

在生物药研发中，抗体药物研发无疑是最受关注的焦点，是增长最快的细分领域之一，已成为生物药中最重要的一大品类。在抗体药物开发过程中，头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。

缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统，重组表达了众多热门靶点的biosimilar参照抗体，便利广大科研工作者进行相关开发过程中的对比研究，同时也可以辅佐验证靶点蛋白的功能活性。

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产品数据展示：

 

活性蛋白检测

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能检测对比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar参照抗体列表

FC-bme100059 muc1 fc1

Biosimilar reference antibodies

Anti-MUC1(gatipotuzumab biosimilar) mAb

SKU:  BME100059     Target:  MUC1

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-bme100224 ly6e elisa1

Biosimilar reference antibodies

Anti-LY6E(RG7841 biosimilar) mAb

SKU:  BME100224     Target:  LY6E

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100207 nkg2d fc1

Biosimilar reference antibodies

Anti-NKG2D(5C5 biosimilar) mAb

SKU:  BME100207     Target:  NKG2D

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100198 cdh17 fc1

Biosimilar reference antibodies

Anti-CDH17(ARB102 biosimilar) mAb

SKU:  BME100198     Target:  CDH17

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100208 steap1 fc1

Biosimilar reference antibodies

Anti-STEAP1(xaluritamig without CD3 biosimilar) mAb

SKU:  BME100208     Target:  STEAP1

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100206 cd19 fc1

Biosimilar reference antibodies

Anti-CD19(loncastuximab biosimilar) mAb

SKU:  BME100206     Target:  CD19

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100205 cd14 fc1

Biosimilar reference antibodies

Anti-CD14(atibuclimab biosimilar) mAb

SKU:  BME100205     Target:  CD14

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100204 ccr5 fc1

Biosimilar reference antibodies

Anti-CCR5(leronlimab biosimilar) mAb

SKU:  BME100204     Target:  CCR5

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100202 pd 1 fc1

Biosimilar reference antibodies

Anti-Canine PD-1(INTERVET 4F12) mAb

SKU:  BME100202     Target:  PD-1

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100196 gprc5d cd3 fc1

Biosimilar reference antibodies

Anti-GPRC5D and CD3(LBL-034 biosimilar) BsAb

SKU:  BME100196     Target:  GPRC5D and CD3

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100193 gprc5d fc1

Biosimilar reference antibodies

Anti-GPRC5D(LBL-034 biosimilar) mAb

SKU:  BME100193     Target:  GPRC5D

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-bme100139 hgf elisa1

Biosimilar reference antibodies

Anti-HGF(ficlatuzumab biosimilar) mAb

SKU:  BME100139     Target:  HGF

Application:  ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-bme100111 lrrc15 fc1

Biosimilar reference antibodies

Anti-LRRC15(samrotamab biosimilar) mAb

SKU:  BME100111     Target:  LRRC15

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100195 CEACAM5 Fig.2 FC 1 1

Biosimilar reference antibodies

Anti-CEACAM5(tusamitamab biosimilar) mAb

SKU:  BME100195     Target:  CEACAM5

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Elisa-BME100189 EPCAM Fig.1 Elisa 1 1

Biosimilar reference antibodies

Anti-EPCAM(IMC001 biosimilar) mAb

SKU:  BME100189     Target:  EPCAM

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100197 B7 H4 Fig.1 FC 1 1

Biosimilar reference antibodies

Anti-B7-H4(SGN-B7H4V biosimilar) mAb

SKU:  BME100197     Target:  B7-H4

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100194 GPNMB Fig.2 FC 1 1

Biosimilar reference antibodies

Anti-GPNMB(glembatumumab biosimilar) mAb

SKU:  BME100194     Target:  GPNMB

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100192 B7 H4 Fig.2 FC 1 1

Biosimilar reference antibodies

Anti-B7-H4(XMT-1660 biosimilar) mAb

SKU:  BME100192     Target:  B7-H4

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100191 ROR1 Fig.2 FC 1 1

Biosimilar reference antibodies

Anti-ROR1(NBE 002 biosimilar) mAb

SKU:  BME100191     Target:  ROR1

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100190 B7 H4 Fig.2 FC 1 1

Biosimilar reference antibodies

Anti-B7-H4(AZD-8205 biosimilar) mAb

SKU:  BME100190     Target:  B7-H4

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100188 STEAP1 Fig.1 FC 1 1

Biosimilar reference antibodies

Anti-STEAP1(Vandortuzumab biosimilar) mAb

SKU:  BME100188     Target:  STEAP1

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100187 GPRC5D Fig.2 FC 1 1

Biosimilar reference antibodies

Anti-GPRC5D(LM305 biosimilar) mAb

SKU:  BME100187     Target:  GPRC5D

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100186 ALPP Fig.2 FC 1 1

Biosimilar reference antibodies

Anti-ALPP(SGN-ALPV biosimilar) mAb

SKU:  BME100186     Target:  ALPP

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100185 FZD10 Fig.2 FC 1 1

Biosimilar reference antibodies

Anti-FZD10(tabituximab biosimilar) mAb

SKU:  BME100185     Target:  FZD10

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100175 AXL Fig.1 FC 1 1

Biosimilar reference antibodies

Anti-AXL(mecbotamab biosimilar) mAb

SKU:  BME100175     Target:  AXL

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100176 CD93 Fig.1 FC 1

Biosimilar reference antibodies

Anti-CD93(biosimilar) mAb

SKU:  BME100176     Target:  CD93

Application:  ELISA, Flow Cyt

Price:50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100174 IGF 1R Fig.1 FC 1

Biosimilar reference antibodies

Anti-IGF-1R(teprotumumab biosimilar) mAb

SKU:  BME100174     Target:  IGF-1R

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100140 CD3E Fig.1 FC 1

Biosimilar reference antibodies

Anti-CD3E(DIMA BM323) mAb

SKU:  BME100140     Target:  CD3E

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100184 EPCAM Fig.1 FC 1

Biosimilar reference antibodies

Anti-EPCAM(oportuzumab biosimilar) mAb

SKU:  BME100184     Target:  EPCAM

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100183 TNFα Fig.1 FC 1

Biosimilar reference antibodies

Anti-TNFa(Certolizumab biosimilar) mAb

SKU:  BME100183     Target:  TNFα

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100182 CEACAM5 Fig.1 FC 1

Biosimilar reference antibodies

Anti-CEACAM5 (Chongqing Precision biosimilar) mAb

SKU:  BME100182     Target:  CEACAM5

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

FC-BME100181 B7 H3 Fig.1 FC 1

Biosimilar reference antibodies

Anti-B7-H3 (TAA06 biosimilar) mAb

SKU:  BME100181     Target:  B7-H3

Application:  ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00