Name: Human TRPC6-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120759

Tag	C-Flag&Strep Tag
Target	TRPC6
Synonyms	N/A
Description	Human TRPC6-Strep full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	Q9Y210
Expression Host	HEK293
Protein Families	Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
Protein Pathways	N/A
Molecular Weight	The human full length TRPC6-Strep protein has a MW of 106.3 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Usage	Research use only
Conjugate	Unconjugated

Human TRPC6-Strep full length protein-synthetic nanodisc