| Tag | C-Flag&Strep Tag |
|---|---|
| Target | |
| Synonyms | GABABR1; GABBR1-3; GB1; GPRC3A |
| Description | Human GABR1-Strep full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | Q9UBS5 |
| Expression Host | HEK293 |
| Protein Families | Druggable Genome, GPCR, Secreted Protein, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Molecular Weight | The human full length GABR1-Strep protein has a MW of 108.3 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | A receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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