| Target | |
|---|---|
| Synonyms | CYSLT1, CYSLTR, CYSLT1R, HMTMF81 |
| Description | Recombinant human CYSLTR1 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q9Y271 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | CYSLTR1(Met1-Ser27) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 29.2 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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