Name: Human 5HT1A-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120161

Tag	C-Flag&Strep Tag
Target	5HT1A
Synonyms	5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; PFMCD
Description	Human 5HT1A-Strep full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	P08908
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
Molecular Weight	The human full length 5HT1A-Strep protein has a MW of 46.1 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	A G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers.
Usage	Research use only
Conjugate	Unconjugated

Human 5HT1A-Strep full length protein-synthetic nanodisc