| Tag | N-His, C-twin-strep |
|---|---|
| Target | |
| Synonyms | 5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; PFMCD |
| Description | Human 5HT1A full length protein-Nanodisc |
| Delivery | 1 week |
| Uniprot ID | P08908 |
| Expression Host | E.coli |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Molecular Weight | The human 5HT1A full length protein has a MW of 50.3kDa |
| Formulation & Reconstitution | Liquid, 50mM HEPES, 150mM NaCl, pH7.5 |
| Storage&Shipping | Store at -80℃, Ship on dry ice. |
| Background | A G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. |
| Purity | >90% |
| Usage | Research use only |
| Conjugate | Unconjugated |
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