| Target | |
|---|---|
| Synonyms | HTPCRX01; HSHTPCRX01; OR9‑21; Olfactory receptor 1J4 |
| Description | Recombinant human OR1J4 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q8NGS1 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | OR1J4(Met1-Ala25) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 29.1 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | OR1J4 encodes an olfactory receptor belonging to the G-protein coupled receptor (GPCR) superfamily. Like other olfactory receptors, OR1J4 is located in the olfactory epithelium, where it interacts with odorant molecules to initiate a neuronal response leading to the perception of smell. It couples to G olf proteins, activating adenylyl cyclase and increasing cAMP, which triggers depolarization of olfactory sensory neurons. OR1J4 is part of a large gene family characterized by single-exon genes and 7-transmembrane domain structures. Beyond olfaction, some olfactory receptors (including OR1J4) are expressed in non-olfactory tissues, suggesting potential roles in cell signaling, migration, and metabolism. |
| Usage | Research use only |
| Conjugate | Unconjugated |
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