| Target | |
|---|---|
| Synonyms | C5A; C5AR; C5R1; CD88 |
| Description | Recombinant Cynomolgus C5AR1 protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | A0A7N9IH82 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | Cynomolgus C5AR1(Met1-Arg34) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 30.0 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Enables G protein-coupled receptor activity and complement component C5a receptor activity. Involved in several processes, including complement component C5a signaling pathway; mRNA transcription by RNA polymerase II; and positive regulation of ERK1 and ERK2 cascade. Located in apical part of cell and basolateral plasma membrane. Biomarker of Alzheimer's disease; asthma; chronic obstructive pulmonary disease; rhinitis; and severe acute respiratory syndrome. [provided by Alliance of Genome Resources, Jun 2025] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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