Recombinant Human C5AR1 Protein with C-terminal human Fc tag
C-Human Fc Tag
The protein has a predicted molecular mass of 30.4 kDa after removal of the signal peptide.The apparent molecular mass of C5AR1-hFc is approximately 40-53 kDa due to glycosylation.
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
Research use only
Human C5AR1 Protein, hFc Tag
Price: 10μg ￥636.00 ; 50μg ￥2333.00 ; 100 μg ￥3499.00
SKU： PME100830 分类： ECD Proteins
Figure 1. Human C5AR1 Protein, hFc Tag on SDS-PAGE under reducing condition.