EGFR重组蛋白、流式抗体及稳转细胞株

EGFR（Epidermal Growth Factor Receptor）又称ERBB1，是ERBB受体酪氨酸激酶家族的经典成员。EGFR与EGF、TGF-α等配体结合后发生二聚化并激活胞内激酶区域，进一步启动RAS/MAPK、PI3K/AKT、JAK/STAT 等多条下游信号通路，从而调节细胞增殖、存活、分化和迁移。EGFR的过表达、扩增或突变广泛存在于多种实体瘤中，使其长期以来一直是肿瘤生物学和靶向药物开发中的核心研究对象。除传统受体阻断研究外，EGFR 还被广泛应用于ADC、双/多特异性抗体及细胞治疗等不同技术路径。由于EGFR胞外区包含多个结构域，不同抗体的表位可能直接影响受体阻断、构象变化、内吞及功能特性，因此结构域级别的抗体筛选十分重要。

缔码生物提供完整EGFR ECD及多个胞外结构域的片段重组蛋白、兔单克隆抗体、多种Biosimilar参照抗体、PE/生物素标记产品以及EGFR过表达稳转细胞株。分段蛋白可用于ELISA、抗体筛选、表位定位、竞争结合和结构域识别；流式抗体及稳转细胞株可用于细胞表面表达、FACS、Cell Binding 和候选分子比较，为EGFR抗体及其他靶向分子的发现、表征和功能评价提供配套工具。

ECD Proteins

Human EGFR(25-133) Protein, hFc Tag

SKU: PME101870 Target: EGFR Tag: C-Human Fc tag

Expression Host: HEK293

Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00

ECD Proteins

Human EGFR(446-621) Protein, hFc Tag

SKU: PME101868 Target: EGFR Tag: C-Human Fc tag

Expression Host: HEK293

Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00

ECD Proteins

Human EGFR(313-445) Protein, hFc Tag

SKU: PME101867 Target: EGFR Tag: C-Human Fc tag

Expression Host: HEK293

Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00

ECD Proteins

Human EGFR(301-645) Protein, His Tag

SKU: PME101680 Target: EGFR Tag: C-10×His tag

Expression Host: HEK293

Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00

ECD Proteins

Human EGFR(25-389) Protein, His Tag

SKU: PME101667 Target: EGFR Tag: C-10×His tag

Expression Host: HEK293

Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00

Biosimilar reference antibodies

Anti-EGFR(depatuxizumab biosimilar) mAb

SKU: BME100252 Target: EGFR

Application: ELISA

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Biosimilar reference antibodies

Anti-EGFR(QD6 biosimilar) mAb

SKU: BME100250 Target: EGFR

Application: ELISA, Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

Overexpression Stable Cell Line

Hu_EGFR K562 Cell Line

SKU: CEL100005 Target: EGFR

Application: FACS Data

Price: Inquiry

ECD Proteins

Cynomolgus EGFR Protein, His Tag

SKU: PME-C100036 Target: EGFR Tag: C-10×His tag

Expression Host: HEK293

Price: 10μg ￥799.00; 50μg ￥2666.00 ; 100 μg ￥3999.00

ECD Proteins

Mouse EGFR Protein, His Tag

SKU: PME-M100062 Target: EGFR Tag: C-6×His Tag

Expression Host: HEK293

Price: 10μg ￥636.00 ; 50μg ￥2333.00 ; 100 μg ￥3499.00

Monoclonal Antibodies

Anti-EGFR antibody(DM130); Rabbit mAb

SKU: DME100130 Target: EGFR

Application: ELISA; Flow Cyt

Price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-EGFR antibody(DM129); Rabbit mAb

SKU: DME100129 Target: EGFR

Application: ELISA; Flow Cyt

Price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-EGFR antibody(DM128); Rabbit mAb

SKU: DME100128 Target: EGFR

Application: ELISA; Flow Cyt

Price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

FC-BME100034 Anti EGFR mAbCetuximab biosimilar FLOW Fig2

Biosimilar reference antibodies

Anti-EGFR (Cetuximab biosimilar) mAb

SKU: BME100034 Target: EGFR

Application: ELISA; Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

ECD Proteins

Human EGFR Protein, His Tag

SKU: PME100099 Target: EGFR Tag: C-6×His Tag

Expression Host: HEK293

Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00

Biosimilar reference antibodies

PE-conjugated Anti-EGFR(depatuxizumab biosimilar) mAb

SKU: BME100252P Target: EGFR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-EGFR(QD6 biosimilar) mAb

SKU: BME100250P Target: EGFR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-EGFR (Cetuximab biosimilar) mAb

SKU: BME100034P Target: EGFR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

Biotinylated Anti-EGFR(tomuzotuximab biosimilar) mAb

SKU: BME100702B Target: EGFR

Application: N/A

Price:100μg ￥1699.00

Biosimilar reference antibodies

Biotinylated Anti-EGFR(pimurutamab biosimilar) mAb

SKU: BME100620B Target: EGFR

Application: N/A

Price:100μg ￥1699.00

EGFR重组蛋白、流式抗体及稳转细胞株

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