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CTLA-4/CD152重组蛋白、流式抗体及稳转细胞株
CTLA-4（Cytotoxic T-Lymphocyte-Associated Protein 4），又称CD152，是免疫球蛋白超家族中的抑制性免疫检查点受体，主要在活化T细胞和调节性T细胞（Treg）中表达。CTLA-4与共刺激受体CD28共享CD80和CD86配体，但具有更高的结合亲和力，可竞争性限制CD28共刺激信号，并通过调节抗原呈递细胞与T细胞之间的相互作用降低T细胞活化。与主要作用于外周组织效应阶段的部分免疫检查点不同，CTLA-4在T细胞初始激活和免疫耐受维持过程中发挥重要作用，因此长期以来都是肿瘤免疫、自身免疫及Treg生物学研究中的核心靶点。针对CTLA-4的研究重点通常包括CD80/CD86结合阻断、受体占有、T细胞活化和Fc相关效应等。
缔码生物提供重组人CTLA-4 ECD重组蛋白，包括hFc、mFc-His等形式，可用于CTLA-4/CD80/CD86互作、ELISA、SPR/BLI、候选抗体筛选及亲和力评价。页面还提供多款ELISA/Flow Cyt验证兔单抗、大量Biosimilar参照抗体以及PE/生物素化形式，可用于细胞表面CTLA-4检测、候选抗体比较和方法开发。人源CTLA-4过表达CHO-S稳转细胞株可进一步用于FACS、Cell Binding、阻断型抗体筛选和细胞水平评价，为CTLA-4抗体发现和免疫检查点机制研究提供蛋白、抗体及细胞层面的配套工具。
Biosimilar reference antibodies
SKU: BME100735 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100726 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100712 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100707 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100689 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100675 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100632 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100577 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100526 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100514 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100500 Target: CTLA-4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100440 Target: CTLA-4
Application: ELISA, Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100022B Target: CTLA-4
Application: ELISA; Flow Cyt
Price:100μg ￥1699.00
Monoclonal Antibodies
SKU: DME100050B Target: CTLA-4
Application: ELISA; Flow Cyt
Price: 100 μg ￥6080.00 ; 500 μg ￥19880.00
Monoclonal Antibodies
SKU: DME100049B Target: CTLA-4
Application: ELISA; Flow Cyt
Price: 100 μg ￥6080.00 ; 500 μg ￥19880.00
