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CDH6重组蛋白、抗体及稳转细胞株
钙粘附蛋白6（Cadherin-6，CDH6），又称为胎儿肾钙粘蛋白或K-钙黏蛋白，是II型经典Cadherin家族成员，属于钙依赖性单次跨膜细胞黏附分子。CDH6在胚胎发育、肾脏和神经系统形成以及组织形态发生过程中发挥重要作用，其成人正常组织表达具有一定限制性，而在部分卵巢、肾脏及其他实体瘤中可出现异常升高。由于CDH6位于细胞表面并具有相对较大的胞外区域，因此近年来受到抗体及ADC等靶向药物研究的持续关注。对于ADC类候选分子而言，除了抗体结合活性，还需要重点评价细胞表面识别、内吞效率及后续载荷介导的细胞杀伤，因此从重组蛋白筛选到细胞水平功能验证通常需要多种工具配合。更多关于CDH6结构与作用>>
缔码生物针对CDH6提供不同胞外域的重组蛋白、兔单克隆抗体、Biosimilar参照抗体、PE/生物素标记产品、CDH6过表达稳转细胞株以及DiSliceX™肿瘤组织切片。ECD蛋白适用于抗体筛选、结合分析和表位研究；流式抗体及稳转细胞株可用于细胞表面结合、FACS和候选分子评价；组织切片可用于IHC和组织表达分析。此外，缔码已获得多个CDH6先导抗体，其中包含人/猴交叉反应候选分子，部分可进一步开展内吞及细胞杀伤验证，并衔接人源化、亲和力成熟等抗体工程服务。
ECD Proteins
SKU: PME101674 Target: CDH6 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2700.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME101673 Target: CDH6 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2700.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME101672 Target: CDH6 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2700.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME101671 Target: CDH6 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2700.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME101670 Target: CDH6 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2700.00 ; 100 μg ￥3999.00
Overexpression Stable Cell Line
SKU: CEL100055 Target: CDH6
Application: FACS Data
Price: Inquiry
DiSliceX
SKU: SLI100004 Target: ADAM9, AFP, ALB, ANGPTL3, B7H3, CD112, CD24, CDH6, CLDN6, CLU, CXADR, GPC3, HER3, MSLN, PRLR, SCF
Application: IHC
Price: 2 slides ￥899.00
Biosimilar reference antibodies
SKU: BME100234 Target: CDH6
Application: ELISA, Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100232 Target: CDH6
Application: ELISA, Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
ECD Proteins
SKU: PME-M100112 Target: CDH6 Tag: C-10×His tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2700.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME-C100044 Target: CDH6 Tag: C-10×His tag
Expression Host: HEK293
Price: 10μg ￥818.00 ; 50μg ￥2999.00 ; 100 μg ￥4499.00
Monoclonal Antibodies
SKU: DMC100675 Target: CDH6
Application: Flow Cyt; WB
Price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00
ECD Proteins
SKU: PME101111 Target: CDH6 Tag: C-6×His Tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2700.00 ; 100 μg ￥3999.00
Monoclonal Antibodies
SKU: DMC100675P Target: CDH6
Application: Flow Cyt
Price: 100 test ￥3880.00
Biosimilar reference antibodies
SKU: BME100234P Target: CDH6
Application: Flow Cyt
Price: 100 test ￥1360.00
Biosimilar reference antibodies
SKU: BME100232P Target: CDH6
Application: Flow Cyt
Price: 100 test ￥1360.00
Biosimilar reference antibodies
SKU: BME100232B Target: CDH6
Application: Flow Cyt
Price:100μg ￥1699.00
Monoclonal Antibodies
SKU: DMC100675B Target: CDH6
Application: Flow Cyt; WB
Price: 100 μg ￥6080.00 ; 500 μg ￥19880.00
