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CD19全长蛋白抗体与细胞株
CD19，又称为Leu-12，是B细胞谱系最经典的细胞表面分子之一，从较早期 B 细胞发育阶段开始表达，并持续存在于大多数成熟B细胞，而在浆细胞阶段逐渐降低。作为B细胞受体信号复合体系的重要调节分子，CD19可调控BCR激活阈值，并参与B细胞增殖、分化和免疫应答。由于其稳定且相对谱系特异的细胞表面表达，CD19已成为B细胞恶性疾病研究中最成熟的靶点之一，被广泛用于单克隆抗体、ADC、双/多特异性抗体和工程化细胞治疗研究。对于CD19靶向分子而言，除常规ECD结合外，抗体在天然膜构象下的识别能力、不同表位分布、跨物种反应性及细胞结合特性同样非常关键。
缔码生物已建立较完整的CD19产品矩阵，包括不同区域及工程设计的ECD重组蛋白、人/猴源蛋白、生物素化蛋白、PeptiNanodisc和Synthetic Nanodisc两种全长CD19膜蛋白、流式/WB单抗、Biosimilar参照抗体、PE/生物素标记产品、CD19过表达K562稳转细胞株及DiSliceX™组织切片。ECD与全长Nanodisc蛋白可分别支持抗体筛选、表位研究及天然膜构象相关结合验证；稳转细胞株适用于FACS、Cell Binding和功能筛选；组织切片可用于IHC评价。此外，缔码还储备多个CD19先导抗体，可进一步衔接人源化、亲和力成熟和功能验证。
ECD Proteins
SKU: PME102002 Target: CD19 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME102001 Target: CD19 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME100781B Target: CD19 Tag: C-Mouse Fc Avi tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
SKU: PME101558B Target: CD19 Tag: C-Human Fc Avi tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
Full Length Transmembrane Proteins
SKU: FLP400499B Target: CD19 Tag: C-Flag&Avi Tag
Expression Host: HEK293
Price:10 μg ￥7700.00 ; 50 μg ￥36300.00 ; 100 μg ￥66550.00
ECD Proteins
SKU: PME-C100089 Target: CD19 Tag: C-10×His tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME101790 Target: CD19 Tag: C-10×His tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
Full Length Transmembrane Proteins
Biotinylated Human CD19 full length protein-synthetic nanodisc
SKU: FLP100499B Target: CD19 Tag: C-Flag&Avi Tag
Expression Host: HEK293
Price: 10 μg ￥6930.00 ; 50 μg ￥33000.00 ; 100 μg ￥60500.00
Overexpression Stable Cell Line
SKU: CEL100102 Target: CD19
Application: FACS Data
Price: Inquiry
Biosimilar reference antibodies
SKU: BME100683 Target: CD19
Application: ELISA, Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
DiSliceX
SKU: SLI100013 Target: B7H2, B7H6, BAFF-R, CD10, CD19, CD205, CD21, CD22, CD23, CD27, CD40, CD48, CD70, CD74, CD79B, CXCR5, ICAM-1, NTB-A, PVRIG
Application: IHC
Price: 2 slides ￥899.00
ECD Proteins
SKU: PME101558 Target: CD19 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME101557 Target: CD19 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
Monoclonal Antibodies
SKU: DMC100804 Target: CD19
Application: WB
price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00
Monoclonal Antibodies
SKU: DMC101150 Target: CD19
Application: Flow Cyt
price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00
Biosimilar reference antibodies
SKU: BME100206 Target: CD19
Application: Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
ECD Proteins
SKU: PME100781 Target: CD19 Tag: C-Mouse Fc Tag
Expression Host: HEK293
Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00
Biosimilar reference antibodies
SKU: BME100094 Target: CD19
Application: ELISA, Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
ECD Proteins
SKU: PME100038 Target: CD19 Tag: C-Human Fc and 6×His Tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
Biosimilar reference antibodies
SKU: BME100051 Target: CD19
Application: ELISA; Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
