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B7-H4/VTCN1重组蛋白、流式抗体及稳转细胞株
B7-H4，又称VTCN1、B7x或B7S1，是B7免疫调节分子家族成员之一，为I型跨膜糖蛋白。B7-H4在多种正常组织中的蛋白水平相对较低，但在卵巢癌、乳腺癌、子宫内膜癌及其他多种实体瘤中可出现异常高表达。其表达不仅可见于肿瘤细胞，还与肿瘤免疫微环境及免疫抑制状态密切相关。已有研究提示，B7-H4可参与抑制T细胞增殖、细胞因子产生和效应功能，从而帮助肿瘤形成免疫逃逸环境。与此同时，其相对较高的肿瘤表面表达和有限的正常组织分布，使 B7-H4同时具有免疫调节靶点和肿瘤表面抗原的双重特征，因此受到单克隆抗体、ADC、双/多特异性分子等研发方向的持续关注。
缔码生物针对B7-H4提供人和猴种属ECD重组蛋白，并包括不同胞外区域和标签形式，可用于ELISA、抗体筛选、表位定位、结合活性及跨种属反应性评价；流式验证的单克隆抗体和多种Biosimilar参照抗体，以及PE/生物素标记形式，可用于细胞表面B7-H4检测、候选抗体比较和方法学开发。B7-H4过表达K562稳转细胞株则适用于FACS、Cell Binding和候选分子细胞水平筛选，并可进一步衔接内吞及功能评价。
ECD Proteins
SKU: PME101577 Target: B7-H4 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
ECD Proteins
SKU: PME101576 Target: B7-H4 Tag: C-Human Fc tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
Monoclonal Antibodies
SKU: DME100188B Target: B7-H4
Application: Flow Cyt
Price: 100 μg ￥6080.00 ; 500 μg ￥19880.00
ECD Proteins
SKU: PME-C100047 Target: B7-H4 Tag: C-10×His tag
Expression Host: HEK293
Price: 10μg ￥821.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00
Biosimilar reference antibodies
SKU: BME100197 Target: B7-H4
Application: Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100192 Target: B7-H4
Application: ELISA, Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100190 Target: B7-H4
Application: ELISA, Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
ECD Proteins
SKU: PME-M100078 Target: B7-H4 Tag: C-6×His Tag
Expression Host: HEK293
Price: 10μg ￥636.00 ; 50μg ￥2333.00 ; 100μg ￥3499.00
Monoclonal Antibodies
SKU: DME100188 Target: B7-H4
Application: ELISA; Flow Cyt
Price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00
ECD Proteins
SKU: PME100053 Target: B7-H4 Tag: C-Human Fc Tag
Expression Host: HEK293
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
Biosimilar reference antibodies
SKU: BME100197P Target: B7-H4
Application: Flow Cyt
Price: 100 test ￥1360.00
Biosimilar reference antibodies
SKU: BME100192P Target: B7-H4
Application: Flow Cyt
Price: 100 test ￥1360.00
Biosimilar reference antibodies
SKU: BME100190P Target: B7-H4
Application: Flow Cyt
Price: 100 test ￥1360.00
Biosimilar reference antibodies
SKU: BME100631B Target: B7-H4
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100509B Target: B7-H4
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100490B Target: B7-H4
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100631 Target: B7-H4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100509 Target: B7-H4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100490 Target: B7-H4
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100197B Target: B7-H4
Application: Flow Cyt
Price:100μg ￥1699.00
