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APP重组蛋白、流式抗体及神经退行性疾病研究工具
APP（Amyloid Precursor Protein）是一种广泛表达的I型跨膜蛋白，在神经元中尤其受到关注。APP可通过α、β和γ-secretase等不同蛋白酶途径被连续切割，产生可溶性APP片段、胞内结构域以及不同长度的amyloid-β（Aβ）肽。非淀粉样途径通常避免Aβ形成，而β/γ-secretase介导的淀粉样途径可产生易聚集的Aβ，其中异常积累和聚集是阿尔茨海默病病理研究的重要组成部分。APP本身还参与神经元发育、突触功能、轴突运输和细胞黏附等过程，因此APP/Aβ体系涉及蛋白加工、聚集、神经毒性和免疫清除等多个研究方向。对于抗体研究而言，不同抗体可能识别完整APP、不同剪切片段或特定Aβ构象，因此抗原选择和表位定义十分重要。
缔码生物提供人源APP重组蛋白，可用于ELISA、抗体筛选和APP相关结合研究；页面还提供单克隆抗体及丰富的参照抗体，包括Flow Cyt、PE或生物素化等形式，可用于细胞相关APP检测、候选抗体比较、捕获实验及神经退行性疾病相关方法建立。针对APP/Aβ项目，建议在实验设计中明确候选抗体的目标形式-完整 APP、可溶性剪切片段还是 Aβ-并根据表位需求选择相应蛋白和检测体系。
Monoclonal Antibodies
SKU: DMC101002 Target: APP
Application: Flow Cyt
Price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00
Biosimilar reference antibodies
SKU: BME100136 Target: APP
Application: Flow Cyt
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
ECD Proteins
SKU: PME100580 Target: APP Tag: C-6×His Tag
Expression Host: HEK293
Price: 10μg ￥668.00 ; 50μg ￥2499.00 ; 100μg ￥3750.00
Biosimilar reference antibodies
SKU: BME100136P Target: APP
Application: Flow Cyt
Price: 100 test ￥1360.00
Biosimilar reference antibodies
SKU: BME100718B Target: APP
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100671B Target: APP
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100660B Target: APP
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100641B Target: APP
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100549B Target: APP
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100479B Target: APP
Application: N/A
Price:100μg ￥1699.00
Biosimilar reference antibodies
SKU: BME100718 Target: APP
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100671 Target: APP
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100660 Target: APP
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100641 Target: APP
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100549 Target: APP
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100479 Target: APP
Application: N/A
Price: 50 μg ￥800.00 ; 100 μg ￥1500.00
Biosimilar reference antibodies
SKU: BME100136B Target: APP
Application: Flow Cyt
Price:100μg ￥1699.00
Monoclonal Antibodies
SKU: DMC101002B Target: APP
Application: Flow Cyt
Price: 100 μg ￥6080.00 ; 500 μg ￥19880.00
