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ACVR2A重组蛋白、流式抗体及稳转细胞株

ACVR2A（Activin A Receptor Type 2A）是TGF-β超家族中的II型丝氨酸/苏氨酸激酶受体，能够结合Activin A、Activin B等多种配体，并与相应I型受体形成信号复合物，进一步激活SMAD2/3等下游通路。ACVR2A信号参与细胞增殖、分化、生殖、组织稳态、代谢及肌肉调控等多种生理过程，其异常调节还与肿瘤、生殖系统疾病、肌肉和代谢相关疾病等研究领域密切相关。由于Activin–ACVR2A轴具有典型的配体–受体相互作用特征，ACVR2A不仅适合用于功能性抗体发现，也常用于配体阻断、竞争结合、受体工程及信号通路调节分子的开发。因此，能够区分不同胞外结构区域、评价候选抗体是否影响配体结合，是该靶点早期研究中的重要环节。

针对ACVR2A，缔码生物提供完整ECD及覆盖不同胞外区域的重组蛋白、生物素化蛋白、流式验证单克隆抗体、参照抗体和ACVR2A过表达稳转细胞株。不同区域蛋白可用于ELISA、抗体筛选、表位定位、结构域识别及配体–受体结合研究；生物素化蛋白便于搭建SPR/BLI、捕获及竞争实验；流式抗体和稳转细胞株则可用于细胞表面表达检测、FACS、Cell Binding 和候选抗体筛选。相关工具可进一步支持功能阻断、配体竞争和下游信号评价，加速ACVR2A靶向分子的筛选和机制验证。

elisa-pme101716b acvr2a elisa1

ECD Proteins

Biotinylated Human ACVR2A(20-135) Protein, His Tag

SKU:  PME101716B     Target:  ACVR2A     Tag:  N-10×His Avi Tag

Expression Host:  HEK293

Price: 10μg ￥693.00 ; 50μg ￥2475.00 ; 100μg ￥3476.00

FC-bme100286 acvr2a fc1

Biosimilar reference antibodies

Anti-ACVR2A(LAE102 biosimilar) mAb

SKU:  BME100286     Target:  ACVR2A

Application:  Flow Cyt

Price: 50 μg ￥800.00 ; 100 μg ￥1500.00

sp-pme101716 acvr2a sp1

ECD Proteins

Human ACVR2A(20-135) Protein, His Tag

SKU:  PME101716     Target:  ACVR2A     Tag:  N-10×His tag

Expression Host:  HEK293

Price: 10μg ￥630.00 ; 50μg ￥2250.00 ; 100μg ￥3160.00

sp-pme101709 acvr2a sp1

ECD Proteins

Human ACVR2A(101-135) Protein, mFc Tag

SKU:  PME101709     Target:  ACVR2A     Tag:  C-Mouse Fc tag

Expression Host:  HEK293

Price: 10μg ￥630.00 ; 50μg ￥2250.00 ; 100μg ￥3160.00

sp-pme101708 acvr2a sp1

ECD Proteins

Human ACVR2A(38-106) Protein, mFc Tag

SKU:  PME101708     Target:  ACVR2A     Tag:  C-Mouse Fc tag

Expression Host:  HEK293

Price: 10μg ￥668.00 ; 50μg ￥2300.00 ; 100μg ￥3499.00

sp-pme101707 acvr2a sp1

ECD Proteins

Human ACVR2A(19-42) Protein, mFc Tag

SKU:  PME101707     Target:  ACVR2A     Tag:  C-Mouse Fc tag

Expression Host:  HEK293

Price: 10μg ￥630.00 ; 50μg ￥2250.00 ; 100μg ￥3160.00

antibody-dmc101357 acvr2a fc1

Monoclonal Antibodies

Anti-ACVR2A antibody(15D6), IgG1 Chimeric mAb

SKU:  DMC101357     Target:  ACVR2A

Application:  Flow Cyt

price: 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

sp-pme101650 acvr2a sp1

ECD Proteins

Human ACVR2A(68-88) Protein, mFc Tag

SKU:  PME101650     Target:  ACVR2A     Tag:  C-Mouse Fc tag

Expression Host:  HEK293

Price: 10μg ￥668.00 ; 50μg ￥2300.00 ; 100μg ￥3499.00

fc-cel100097 hu acvr2a cho s cell line flow

Overexpression Stable Cell Line

Hu_ACVR2A CHO-S Cell Line

SKU:  CEL100097     Target:  ACVR2A

Application:  FACS Data

Price: Inquiry

fc-cel100094 m acvr2a cho s cell line flow

Overexpression Stable Cell Line

M_ACVR2A CHO-S Cell Line

SKU:  CEL100094     Target:  ACVR2A

Application:  FACS Data

Price: Inquiry

sp-pme101609 acvr2a sp1

ECD Proteins

Human ACVR2A Protein, mFc Tag

SKU:  PME101609     Target:  ACVR2A     Tag:  C-Mouse Fc tag

Expression Host:  HEK293

Price: 10μg ￥630.00 ; 50μg ￥2250.00 ; 100μg ￥3160.00

sp-pme m100115 acvr2a sp1

ECD Proteins

Mouse ACVR2A Protein, hFc Tag

SKU:  PME-M100115     Target:  ACVR2A     Tag:  C-Human Fc tag

Expression Host:  HEK293

Price: 10μg ￥630.00 ; 50μg ￥2250.00 ; 100μg ￥3160.00

sp-pme101550 acvr2a sp1

ECD Proteins

Human ACVR2A Protein, hFc Tag

SKU:  PME101550     Target:  ACVR2A     Tag:  C-Human Fc tag

Expression Host:  HEK293

Price: 10μg ￥630.00 ; 50μg ￥2250.00 ; 100μg ￥3160.00

占位

Monoclonal Antibodies

PE-conjugated Anti-ACVR2A antibody(15D6), IgG1 Chimeric mAb

SKU:  DMC101357P     Target:  ACVR2A

Application:  Flow Cyt

Price: 100 test ￥3880.00

占位

Monoclonal Antibodies

Biotinylated Anti-ACVR2A antibody(15D6), IgG1 Chimeric mAb

SKU:  DMC101357B     Target:  ACVR2A

Application:  Flow Cyt

Price: 100 μg ￥6080.00 ; 500 μg ￥19880.00

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