Tag | C-Flag Tag |
---|---|
Target | |
Synonyms | HPTPZ; HPTPzeta; phosphacan; PTP-ZETA; PTP18; PTPRZ; PTPZ; R-PTP-zeta-2; RPTPB; RPTPbeta |
Description | Human PTPRZ1 full length protein-synthetic nanodisc |
Delivery | In Stock |
Uniprot ID | P23471 |
Expression Host | HEK293 |
Protein Families | Druggable Genome, Phosphatase, Transmembrane |
Protein Pathways | Epithelial cell signaling in Helicobacter pylori infection |
Molecular Weight | The human full length PTPRZ1 protein has a MW of 254.6 kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades. |
Usage | Research use only |
Conjugate | Unconjugated |
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