| Target | |
|---|---|
| Synonyms | CLN1;INCL;PPT |
| Description | Recombinant human PPT protein with C-terminal human Fc tag |
| Delivery | Under development |
| Uniprot ID | P20366 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | PPT (Arg58-Met107) hFc(Glu99-ALA330) |
| Molecular Weight | The protein has a predicted molecular mass of 30.69 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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