| Tag | C-Flag&Strep Tag | 
|---|---|
| Target | |
| Synonyms | N/A | 
| Description | Human KCD17-Strep full length protein-synthetic nanodisc | 
| Delivery | 6~8weeks | 
| Uniprot ID | Q8N5Z5 | 
| Expression Host | HEK293 | 
| Protein Families | Ion Channels: Other | 
| Protein Pathways | N/A | 
| Molecular Weight | The human full length KCD17-Strep protein has a MW of 35.7 kDa | 
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. | 
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | 
| Background | This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD)-containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26. [provided by RefSeq, Nov 2016] | 
| Usage | Research use only | 
| Conjugate | Unconjugated | 
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