| Target | |
|---|---|
| Synonyms | Claudin-2;SP82 |
| Description | Recombinant human CLDN2 protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P57739 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | CLDN2(Ser29-Gln78) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of CLDN2-hFc is approximately 25-35 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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