| Target | |
|---|---|
| Synonyms | CALC1;CALCA;CGRP-alpha;CGRP-I;CGRP1;CT;KC;PCT |
| Description | Recombinant Human CGRP Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P06881 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | CGRP(Ala83-Phe119) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 29.9 kDa after removal of the signal peptide. The apparent molecular mass of CGRP-hFc is approximately 25-35 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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