| Tag | C-strep-His |
|---|---|
| Target | |
| Synonyms | CLD1; ILVASC; SEMP1 |
| Description | Human CLDN1 full length protein-Detergent |
| Delivery | 1 week |
| Uniprot ID | O95832 |
| Expression Host | E.coli |
| Protein Families | Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Tight junction |
| Molecular Weight | The human CLDN1 full length protein has a MW of 25kDa |
| Formulation & Reconstitution | Liquid, 50mM HEPES, 150mM NaCl, 0.06M, 0.012%CHS, pH7.5 |
| Storage&Shipping | Store at -80℃, Ship on dry ice. |
| Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008] |
| Purity | >80% |
| Usage | Research use only |
| Conjugate | Unconjugated |
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