Biotinylated Human CCR2 full length protein-synthetic nanodisc

Name: Biotinylated Human CCR2 full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP100028B

Price: 10 μg ￥6930.00 ; 50 μg ￥33000.00 ; 100 μg ￥60500.00

SKU： FLP100028B 分类： Full Length Transmembrane Proteins

Datasheet

MSDS

Each batch undergoes strict quality control and contact us to know the details.

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Tag	C-Flag and Avi Tag
Target	CCR2
Synonyms	CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; PCLUD; CMKBR2; MCP-1-R; CC-CKR-2
Description	Biotinylated Human CCR2 full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	P41597
Expression Host	HEK293
Protein Families	Transmembrane
Protein Pathways	AKT Signaling Pathway, Autophagy pathway, Jak-Stat Signaling Pathway
Molecular Weight	The human full length CCR2 Protein has a MW of 46.7 kDa.
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
Usage	Research use only
Conjugate	Biotinylated

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Figure 1. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Biotinylated Human CCR2 full length protein-synthetic nanodisc (FLP100028B) can bind Anti-Flag Rabbit mAb in a linear range of 0.13-16 ng/mL.

Figure 2. ELISA plate pre-coated by 1 μg/mL (100 μL/well) Streptavidin can bind Biotinylated Human CCR2 full length protein-synthetic nanodisc (FLP100028B) in a linear range of 16-400 ng/mL. In order to specifically detect FLP100028B, Anti-Flag Rabbit antibody was used as detection antibody.

Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Anti-flag Rabbit mAb can bind Biotinylated Human CCR2 full length protein-synthetic nanodisc (FLP100028B) in a linear range of 16-400 ng/mL. In order to specifically detect FLP100028B, HRP Conjugated Streptavidin was used as detection antibody.

Figure 4. Biotinylated Human CCR2-Nanodisc, Flag Tag on SDS-PAGE

Biotinylated Human CCR2 full length protein-synthetic nanodisc

Product Data Negative control Dima FAQ

图片 Negative control Dima FAQ

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