Tag | C-Flag and Avi Tag |
---|---|
Target | |
Synonyms | CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; PCLUD; CMKBR2; MCP-1-R; CC-CKR-2 |
Description | Biotinylated Human CCR2 full length protein-synthetic nanodisc |
Delivery | In Stock |
Uniprot ID | P41597 |
Expression Host | HEK293 |
Protein Families | Transmembrane |
Protein Pathways | AKT Signaling Pathway, Autophagy pathway, Jak-Stat Signaling Pathway |
Molecular Weight | The human full length CCR2 Protein has a MW of 46.7 kDa. |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017] |
Usage | Research use only |
Conjugate | Biotinylated |
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