Clone ID | 8C4 |
---|---|
Target | |
Synonyms | CD120b;p75;p75TNFR;TBPII;TNF-R-II;TNF-R75;TNFBR;TNFR1B;TNFR2;TNFR80 |
Host Species | Rabbit |
Description | Anti-TNFRSF1B antibody(8C4); IgG1 Chimeric mAb |
Delivery | In Stock |
Uniprot ID | P20333 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1/100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008] |
Usage | Research use only |
Conjugate | Unconjugated |
Anti-TNFRSF1B antibody(8C4); IgG1 Chimeric mAb
Price: 10μg ¥690.00 ; 50μg ¥2280.00 ; 100 μg ¥4080.00 ; 500 μg ¥13280.00
Product Data
图片
Figure 1. Flow cytometry analysis with Anti-TNFRSF1B (8C4) mAb on Expi293 cells transfected with human TNFRSF1B (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
相关产品
Biosimilar reference antibodies
SKU: BME100493P Target: TNFRSF1B
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100493 Target: TNFRSF1B
Application: N/A
Price: 50 μg ¥800.00 ; 100 μg ¥1500.00
Monoclonal Antibodies
PE-conjugated Anti-TNFRSF1B antibody(8C4); IgG1 Chimeric mAb
SKU: DMC101037P Target: TNFRSF1B
Application: Flow Cyt
Price: 100 test ¥3880.00
ECD Proteins
SKU: PME101265 Target: TNFRSF1B
Price: 10μg ¥636.00 ; 50μg ¥2333.00 ; 100μg ¥3499.00
Biosimilar reference antibodies
SKU: BME100493B Target: TNFRSF1B
Application: N/A
Price: 50 μg ¥890.00 ; 100 μg ¥1699.00