| Clone ID | 2F4 |
|---|---|
| Target | |
| Synonyms | AG-2;hAG-2;HPC8 |
| Host Species | Rabbit |
| Description | Anti-AGR2 antibody(2F4), Rabbit mAb |
| Delivery | In Stock |
| Uniprot ID | O95994 |
| IgG type | Rabbit mAb |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA |
| Recommended Dilutions | ELISA 1/5000-10000 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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