Biosimilar参照抗体

在生物药研发中，抗体药物研发无疑是最受关注的焦点，是增长最快的细分领域之一，已成为生物药中最重要的一大品类。在抗体药物开发过程中，头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。

缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统，重组表达了众多热门靶点的biosimilar参照抗体，便利广大科研工作者进行相关开发过程中的对比研究，同时也可以辅佐验证靶点蛋白的功能活性。

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产品数据展示：

活性蛋白检测

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能检测对比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar参照抗体列表

Biosimilar reference antibodies

PE-conjugated Anti-CD40 Ligand (ruplizumab biosimilar) mAb

SKU: BME100042P Target: CD40 Ligand

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-IL6R (tocilizumab biosimilar) mAb

SKU: BME100041P Target: IL6R

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-4-1BB (utomilumab biosimilar) mAb

SKU: BME100037P Target: 4-1BB

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-ICAM-1 (bersanlimab biosimilar) mAb

SKU: BME100036P Target: ICAM-1

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CEACAM5 (labetuzumab biosimilar) mAb

SKU: BME100035P Target: CEACAM5

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-IL17RA (brodalumab biosimilar) mAb

SKU: BME100038P Target: IL17RA

Application: Flow Cyt

Price: 100 test ￥1360.00

FC-bme100034p egfr fc1

Biosimilar reference antibodies

PE-conjugated Anti-EGFR (Cetuximab ) mAb

SKU: BME100034P Target: EGFR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-AXL (enapotamab biosimilar) mAb

SKU: BME100033P Target: AXL

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TNFRSF10B (tigatuzumab biosimilar) mAb

SKU: BME100032P Target: TNFRSF10B

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TweakR (enavatuzumab biosimilar) mAb

SKU: BME100031P Target: TweakR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD52 (alemtuzumab biosimilar) mAb

SKU: BME100030P Target: CD52

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD22 (pinatuzumab biosimilar) mAb

SKU: BME100029P Target: CD22

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-BCMA (belantamab biosimilar) mAb

SKU: BME100028P Target: BCMA

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TIGIT (vibostolimab biosimilar) mAb

SKU: BME100027P Target: TIGIT

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TIGIT (tiragolumab biosimilar) mAb

SKU: BME100026P Target: TIGIT

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD20 (rituximab biosimilar) mAb

SKU: BME100025P Target: CD20

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CA9 (girentuximab biosimilar) mAb

SKU: BME100040P Target: CA9

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-NKG2D (tesnatilimab biosimilar) mAb

SKU: BME100039P Target: NKG2D

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TIGIT (etigilimab biosimilar) mAb

SKU: BME100024P Target: TIGIT

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CTLA-4 (ipilimumab biosimilar) mAb

SKU: BME100022P Target: CTLA-4

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-Mesothelin (amatuximab biosimilar) mAb

SKU: BME100021P Target: MSLN

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD40 (iscalimab biosimilar) mAb

SKU: BME100020P Target: CD40

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-EPHA3 (ifabotuzumab biosimilar) mAb

SKU: BME100019P Target: EPHA3

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD27 (varlilumab biosimilar) mAb

SKU: BME100018P Target: CD27

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD30 (brentuximab biosimilar) mAb

SKU: BME100017P Target: CD30

Application: Flow Cyt

Price: 100 test ￥1360.00

FC-bme100016p bcma fc1

Biosimilar reference antibodies

PE-conjugated Anti-BCMA (biosimilar) mAb

SKU: BME100016P Target: BCMA

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD33 (gemtuzumab biosimilar) mAb

SKU: BME100015P Target: CD33

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD138 (indatuximab biosimilar) mAb

SKU: BME100014P Target: CD138

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-SARS-CoV (CR3022) mAb

SKU: BME100013P Target: SARS

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-ICOS (vopratelimab biosimilar) mAb

SKU: BME100012P Target: ICOS

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-B7-H3 (enoblituzumab biosimilar) mAb

SKU: BME100010P Target: B7-H3

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-PDL1 (atezolizumab biosimilar) mAb

SKU: BME100009P Target: PDL1

Application: Flow Cyt

Price: 100 test ￥1360.00