Biosimilar参照抗体

在生物药研发中，抗体药物研发无疑是最受关注的焦点，是增长最快的细分领域之一，已成为生物药中最重要的一大品类。在抗体药物开发过程中，头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。

缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统，重组表达了众多热门靶点的biosimilar参照抗体，便利广大科研工作者进行相关开发过程中的对比研究，同时也可以辅佐验证靶点蛋白的功能活性。

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产品数据展示：

活性蛋白检测

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Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.

流式功能检测对比

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Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Biosimilar参照抗体列表

Biosimilar reference antibodies

PE-conjugated Anti-CCR4(mogamulizumab biosimilar) mAb

SKU: BME100086P Target: CCR4

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-IL7RA(lusvertikimab biosimilar) mAb

SKU: BME100084P Target: IL7RA

Application: Flow Cyt

Price: 100 test ￥1360.00

FC-bme100083p gpc3 fc1

Biosimilar reference antibodies

PE-conjugated Anti-GPC3(codrituzumab biosimilar) mAb

SKU: BME100083P Target: GPC3

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CLDN6 (IMAB027) mAb

SKU: BME100082P Target: CLDN6

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-B7-H2(prezalumab biosimilar) mAb

SKU: BME100081P Target: B7-H2

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TSHR (K1-70) mAb

SKU: BME100080P Target: TSHR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TSHR (M22) mAb

SKU: BME100079P Target: TSHR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-B7-H4(alsevalimab biosimilar) mAb

SKU: BME100078P Target: B7H4

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-SELP(crizanlizumab biosimilar) mAb

SKU: BME100077P Target: SELP

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD47(lemzoparlimab biosimilar) mAb

SKU: BME100076P Target: CD47

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-ROR1 (zilovertamab biosimilar) mAb

SKU: BME100073P Target: ROR1

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-DLL3(Rovalpituzumab biosimilar) mAb

SKU: BME100068P Target: DLL3

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-GITR(ragifilimab biosimilar) mAb

SKU: BME100065P Target: GITR

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-ADAM9 (biosimilar) mAb

SKU: BME100064P Target: ADAM9

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-Her2 (trastuzumab biosimilar) mAb

SKU: BME100048P Target: Her2

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CCR8(10A11) mAb

SKU: BME100063P Target: CCR8

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD47 (magrolimab biosimilar;IgG1) mAb

SKU: BME100050P Target: CD47

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-ITGA4 (natalizumab biosimilar) mAb

SKU: BME100074P Target: ITGA4

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-GPRC5D (Talquetamab without CD3 biosimilar) mAb

SKU: BME100072P Target: GPRC5D

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TNFSF11 (denosumab biosimilar)mAb

SKU: BME100058P Target: TNFSF11

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-LAG3 (relatlimab biosimilar)mAb

SKU: BME100062P Target: LAG3

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-VEGFR2 (ramucirumab biosimilar)mAb

SKU: BME100060P Target: VEGFR2

Application: Flow Cyt

Price: 100 test ￥1360.00

FC-bme100057p her3 fc1

Biosimilar reference antibodies

PE-conjugated Anti-HER3 (patritumab biosimilar)mAb

SKU: BME100057P Target: HER3

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-TNFa(Adalimumab biosimilar) mAb

SKU: BME100056P Target: TNFA

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CSF1R(cabiralizumab biosimilar) mAb

SKU: BME100055P Target: CSF1R

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-BTLA (icatolimab biosimilar)mAb

SKU: BME100054P Target: BTLA

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-OX40( ivuxolimab biosimilar)mAb

SKU: BME100053P Target: OX40

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-IL-4RA (dupilumab biosimilar)mAb

SKU: BME100052P Target: IL4RA

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD19 (inebilizumab biosimilar)mAb

SKU: BME100051P Target: CD19

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-CD37 (naratuximab biosimilar) mAb

SKU: BME100046P Target: CD37

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-BAFF (belimumab biosimilar) mAb

SKU: BME100044P Target: BAFF

Application: Flow Cyt

Price: 100 test ￥1360.00

Biosimilar reference antibodies

PE-conjugated Anti-IL2RA (basiliximab biosimilar) mAb

SKU: BME100043P Target: IL2RA

Application: Flow Cyt

Price: 100 test ￥1360.00