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在生物药研发中,抗体药物研发无疑是最受关注的焦点,是增长最快的细分领域之一,已成为生物药中最重要的一大品类。在抗体药物开发过程中,头对头的质量可比性研究更是重中之重。通常临床阶段及上市抗体药分子是大家首选的对标参照。
缔码生物功能活性蛋白表达平台利用HEK293哺乳动物细胞分泌表达系统,重组表达了众多热门靶点的biosimilar参照抗体,便利广大科研工作者进行相关开发过程中的对比研究,同时也可以辅佐验证靶点蛋白的功能活性。
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PD1, mFc-His tagged protein (PME100025) can bind Anti-PD-1 Neutralizing antibody in a linear range of 0.24-6.49 ng/ml.
Figure 2. HEK293 cell line transfected with irrelevant protein and human PD1 were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
Biosimilar reference antibodies
SKU: BME100102P Target: CD56
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100101P Target: CXCR4
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100100P Target: CEACAM6
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100097P Target: IL1A
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100085P Target: NKG2A
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100094P Target: CD19
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100091P Target: GFRA3
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
PE-conjugated Anti-FCRL5(cevostamab biosimilar without anti-CD3 portion) mAb
SKU: BME100089P Target: FCRL5
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100087P Target: CCR2
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100086P Target: CCR4
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100084P Target: IL7RA
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100083P Target: GPC3
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100082P Target: CLDN6
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100081P Target: B7-H2
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100080P Target: TSHR
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100079P Target: TSHR
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100078P Target: B7H4
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100077P Target: SELP
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100076P Target: CD47
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100073P Target: ROR1
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100068P Target: DLL3
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100065P Target: GITR
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100064P Target: ADAM9
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100048P Target: Her2
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100063P Target: CCR8
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100050P Target: CD47
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100074P Target: ITGA4
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
PE-conjugated Anti-GPRC5D (Talquetamab without CD3 biosimilar) mAb
SKU: BME100072P Target: GPRC5D
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100058P Target: TNFSF11
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100062P Target: LAG3
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100060P Target: VEGFR2
Application: Flow Cyt
Price: 100 test ¥1360.00
Biosimilar reference antibodies
SKU: BME100057P Target: HER3
Application: Flow Cyt
Price: 100 test ¥1360.00