Tag | C-Flag Tag |
---|---|
Target | |
Synonyms | P2X7 |
Description | Human P2RX7 full length protein-synthetic nanodisc |
Delivery | 3-4 weeks |
Uniprot ID | Q99572 |
Expression Host | HEK293 |
Protein Families | Druggable Genome, Ion Channels: ATP Receptors, Transmembrane |
Protein Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
Molecular Weight | The human full length P2RX7 protein has a MW of 68.4 kDa |
Formulation & Reconstitution | |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010] |
Usage | Research use only |
Conjugate | Unconjugated |
服务热线
400-006-0995
18062749453