| Target | |
|---|---|
| Synonyms | HG20, DEE59, GPR51, EIEE59, GPRC3B, NDPLHS, GABABR2, HRIHFB2099 |
| Description | Recombinant human GABBR2 Protein with C-terminal 10×His tag |
| Delivery | In Stock |
| Uniprot ID | O75899 |
| Expression Host | HEK293 |
| Tag | C-10×His tag |
| Molecular Characterization | GABBR2(Trp42-Ser478) 10×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 50.9 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage&Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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