| Clone ID | DMC390 |
|---|---|
| Target | |
| Synonyms | BETA-HFR; FBP; FBP:PL-1; FOLR1; FR-BETA; FR-P3; FRbeta |
| Host Species | Rabbit |
| Description | PE-conjugated Anti-FOLR2 antibody(DMC390); IgG1 Chimeric mAb |
| Delivery | Under Development |
| Uniprot ID | P14207 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
| Storage & Shipping | Store at 2°C-8°C for 6 months |
| Background | The protein encoded by this gene is a member of the folate receptor (FOLR) family; and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives; and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins; respectively. Although this protein was originally thought to be specific to placenta; it can also exist in other tissues; and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. |
| Usage | Research use only |
| Conjugate | PE-conjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scr |
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