| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | PEN; PEN.; TSPAN-33 |
| Description | Human TSPAN33 full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | Q86UF1 |
| Expression Host | HEK293 |
| Protein Families | Transmembrane |
| Protein Pathways | N/A |
| Molecular Weight | The human full length TSPAN33 protein has a MW of 31.5 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862). |
| Usage | Research use only |
| Conjugate | Unconjugated |
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