| Target | |
|---|---|
| Synonyms | APO2;CD261;DR4;TRAILR-1;TRAILR1 |
| Description | Recombinant human TNFRSF10A protein with C-terminal human Fc tag |
| Delivery | Under development |
| Uniprot ID | O00220 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | TNFRSF10A (Ala24-Asn239) hFc (Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 49.28 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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