Recombinant human TIGIT Protein with C-terminal mouse Fc tag
C-Mouse Fc Tag
The protein has a predicted molecular mass of 39.24 kDa after removal of the signal peptide.The apparent molecular mass of TIGIT-mFc is approximately 40-53 kDa due to glycosylation.
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Research use only
Human TIGIT Protein, mFc Tag
Price: 10μg ￥727.00 ; 50μg ￥2666.00 ; 100 μg ￥3999.00
Figure 1. Human TIGIT Protein, mFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human TIGIT, mFc tagged protein (PME100505) can bind Anti-TIGIT Neutralizing antibody（BME100024） in a linear range of 0.13-16.0 ng/ml.