Name: Human SCN5A-Strep full length protein-synthetic nanodisc - 专注肿瘤免疫
SKU: FLP120726

Tag	C-Flag&Strep Tag
Target	SCN5A
Synonyms	CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Description	Human SCN5A-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	Q14524
Expression Host	HEK293
Protein Families	Ion Channels: Sodium
Protein Pathways	N/A
Molecular Weight	The human full length SCN5A-Strep protein has a MW of 226.9 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated

Human SCN5A-Strep full length protein-synthetic nanodisc