| Target | |
|---|---|
| Synonyms | GPCR101, XLRG1, G protein-coupled receptor 101 |
| Description | Recombinant human GPR101 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q96P66 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | GPR101(Met1-Arg34) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 29.8 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | GPR101 (G protein-coupled receptor 101) is a G-protein coupled receptor (GPCR) primarily expressed in the pituitary gland, hypothalamus, and brain tissues. It couples to Gs proteins, activating adenylyl cyclase and increasing intracellular cAMP, influencing hormone secretion, growth regulation, and pituitary function. Dysregulation or overexpression of GPR101 is associated with X-linked acrogigantism (XLAG) and pituitary hyperplasia, making it a potential therapeutic target for endocrine disorders. |
| Usage | Research use only |
| Conjugate | Unconjugated |
服务热线
400-006-0995
18062749453
