CEACAM-5;D66e;EA;econium antigen 100
Recombinant human CEACAM5 protein with C-terminal 6×His tag
CEACAM5(Lys35-Ala685) 6×His tag
The protein has a predicted molecular mass of 72.2 kDa after removal of the signal peptide. The apparent molecular mass of CEACAM5-His is approximately 100-130 kDa due to glycosylation.
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
|Formulation & Reconstitution||
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
|Storage & Shipping||
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Research use only
Human CEACAM5 Protein, His Tag
Price: 10μg ￥782.00 ; 50μg ￥2866.00 ; 100 μg ￥4299.00
Figure 1. Human CEACAM5 Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CEACAM5, His tagged protein (PME100071) can bind Anti-CEACAM5 Antibody (BME100035) in a linear range of 2.56-320 ng/ml.
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CEACAM5 Protein, His Tag (PME100071) can bind Anti-CEACAM5(tusamitamab biosimilar) mAb (BME100195) in a linear range of 0.64–16 ng/mL.