| Target | |
|---|---|
| Synonyms | BDA2;BMP2A;SSFSC;SSFSC1 |
| Description | Recombinant Human BMP2 Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | P12643 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | BMP2(Gln283-Arg396) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 39.0 kDa after removal of the signal peptide. The apparent molecular mass of BMP2-hFc is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016] |
| Usage | Research use only |
| Conjugate | Unconjugated |
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